C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glycine receptor, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109738 GLRB 9606 + 4:157076057-157172090 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264428 GLRB-001 157076057-157172090 protein_coding
  ENST00000506411 GLRB-003 157076204-157138872 nonsense_mediated_decay
  ENST00000509282 GLRB-002 157076403-157170806 protein_coding
  ENST00000510970 GLRB-006 157136365-157138900 retained_intron
  ENST00000512619 GLRB-005 157076195-157170905 protein_coding
  ENST00000515642 GLRB-004 157076166-157136511 nonsense_mediated_decay
  ENST00000541722 GLRB-201 157076125-157172090 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264428ENST00000506411ENST00000509282ENST00000510970ENST00000512619ENST00000515642ENST00000541722
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264428 0.054±0.00 0.716±0.00 N/A 13.361±4.61 N/A 1.002±0.00 0.197±0.00 N/A 0.298±0.20 N/A 0.049±0.00 0.247±0.18 0.136±0.06 0.259±0.09
ENST00000506411 N/A N/A 0.310±0.00 N/A 0.179±0.00 0.601±0.00 0.640±0.00 0.245±0.00 N/A N/A N/A N/A N/A N/A
ENST00000509282 0.179±0.00 1.005±0.00 N/A 14.580±0.00 1.381±0.00 0.997±0.00 0.921±0.76 0.561±0.00 N/A 0.441±0.24 0.182±0.00 0.463±0.25 0.774±0.18 0.421±0.04
ENST00000510970 N/A N/A 0.558±0.00 N/A N/A N/A N/A N/A N/A 1.315±0.00 0.385±0.00 0.107±0.00 N/A N/A
ENST00000512619 N/A N/A N/A N/A N/A N/A N/A N/A 0.274±0.00 0.833±0.00 N/A N/A 0.419±0.00 N/A
ENST00000515642 0.324±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.393±0.00 N/A N/A N/A N/A
ENST00000541722 0.066±0.00 N/A N/A N/A 0.362±0.00 0.289±0.00 0.504±0.00 0.412±0.00 0.126±0.00 0.263±0.00 N/A 0.059±0.00 0.174±0.00 0.374±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006DW CIL_0006DW_0002 CGP 4:156760454-157172090
CIL_0006DX CIL_0006DX_0002 CGP 4:157076057-157366075

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001964 IMP startle response
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0006810 IEA transport
GO:0006811 IDA:IEA ion transport
GO:0007218 IDA neuropeptide signaling pathway
GO:0007268 IMP synaptic transmission
GO:0007340 IEA acrosome reaction
GO:0007399 IMP nervous system development
GO:0007601 IEA visual perception
GO:0007628 IEA adult walking behavior
GO:0008144 IEA drug binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016594 IMP glycine binding
GO:0016933 IMP extracellular-glycine-gated ion channel activity
GO:0016934 TAS extracellular-glycine-gated chloride channel activity
GO:0030054 IEA cell junction
GO:0034220 TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0042391 IEA regulation of membrane potential
GO:0045211 IEA postsynaptic membrane
GO:0050905 IEA neuromuscular process
GO:0051291 IEA protein heterooligomerization
GO:0055085 TAS transmembrane transport
GO:0060012 IEA synaptic transmission, glycinergic
GO:0060013 IEA righting reflex
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052769 glrbb glycine receptor, beta b protein_coding Danio_rerio
ENSDARG00000052782 glrba gylcine receptor, beta a protein_coding Danio_rerio
ENSMUSG00000028020 Glrb glycine receptor, beta subunit protein_coding Mus_musculus

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