C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028496 Mllt3 10090 - 4:87769925-88033364 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000078090 Mllt3-001 87769925-88033364 protein_coding
  ENSMUST00000126353 Mllt3-003 87772673-87806314 protein_coding
  ENSMUST00000128930 Mllt3-006 87791853-88033281 processed_transcript
  ENSMUST00000134555 Mllt3-007 87832781-87874542 processed_transcript
  ENSMUST00000141526 Mllt3-005 87837419-88032813 retained_intron
  ENSMUST00000142454 Mllt3-004 87841084-88032813 nonsense_mediated_decay
  ENSMUST00000148059 Mllt3-010 87773953-87806294 protein_coding
  ENSMUST00000149357 Mllt3-002 87773916-87806323 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000078090ENSMUST00000126353ENSMUST00000128930ENSMUST00000142454ENSMUST00000148059ENSMUST00000149357
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000078090 1.470±0.57 1.526±0.39 1.333±0.03 6.114±4.37 1.624±0.49 2.118±0.28 0.545±0.08 0.844±0.22 1.471±1.55 1.884±0.26 3.163±0.28 1.944±0.87 0.439±0.07 0.255±0.08
ENSMUST00000126353 2.379±1.20 N/A 2.115±0.12 N/A 6.660±1.69 4.826±0.60 0.921±0.19 1.465±0.15 4.379±4.73 3.829±0.62 8.131±1.39 2.153±0.52 1.410±0.86 N/A
ENSMUST00000128930 N/A N/A N/A N/A 1.950±0.13 2.100±0.12 0.765±0.11 N/A 0.261±0.09 N/A N/A 1.397±0.03 1.627±0.00 1.207±0.17
ENSMUST00000142454 2.079±0.00 1.738±0.64 N/A N/A 2.094±0.22 3.377±0.82 N/A 1.315±0.26 N/A 1.762±0.00 N/A 3.522±1.20 N/A 1.709±1.02
ENSMUST00000148059 N/A N/A N/A 21.491±0.00 N/A N/A N/A N/A N/A N/A N/A 29.585±0.00 24.748±3.35 20.561±0.00
ENSMUST00000149357 N/A N/A N/A 7.508±0.00 5.026±0.59 N/A 1.443±0.31 N/A 27.840±17.79 N/A 29.661±2.56 11.634±0.00 5.559±1.74 3.531±1.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007D2 CIL_0007D2_0002 CGP 4:86983124-88033364
CIL_0005UZ CIL_0005UZ_0003 CGP 4:87769925-88411011

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007379 IMP segment specification
GO:0008023 IEA transcription elongation factor complex
GO:0009952 IMP anterior/posterior pattern specification
GO:0070062 IEA extracellular vesicular exosome
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:2000096 IEA positive regulation of Wnt signaling pathway, planar cell polarity pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006754 mllt3 myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog (Drosophila) protein_coding Danio_rerio
ENSG00000171843 MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 protein_coding Homo_sapiens

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