C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171843 MLLT3 9606 - 9:20341665-20622543 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380321 MLLT3-002 20346406-20382469 protein_coding
  ENST00000380323 MLLT3-006 20345077-20382487 processed_transcript
  ENST00000380338 MLLT3-001 20341665-20622543 protein_coding
  ENST00000468513 MLLT3-004 20360742-20411962 processed_transcript
  ENST00000469261 MLLT3-007 20346293-20363569 processed_transcript
  ENST00000475957 MLLT3-008 20362705-20622440 processed_transcript
  ENST00000488705 MLLT3-005 20346353-20382471 processed_transcript
  ENST00000491137 MLLT3-003 20360753-20382452 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380321ENST00000380323ENST00000380338ENST00000475957
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380321 0.997±0.00 N/A N/A 3.634±0.00 N/A 5.179±0.58 1.351±0.09 2.674±0.00 N/A 2.801±0.34 0.560±0.00 3.090±0.40 2.291±0.93 2.266±0.68
ENST00000380323 0.672±0.00 1.361±0.00 N/A 2.209±0.00 1.229±0.05 2.116±0.02 0.647±0.22 0.803±0.62 0.104±0.00 1.004±0.00 N/A 1.727±0.44 1.435±0.33 0.730±0.47
ENST00000380338 0.425±0.00 0.508±0.00 0.866±0.00 1.484±0.52 0.620±0.16 1.054±0.37 0.255±0.02 0.408±0.37 2.019±0.00 0.861±0.34 0.175±0.00 0.795±0.28 0.342±0.08 0.411±0.28
ENST00000475957 0.393±0.00 N/A 0.636±0.00 N/A N/A N/A N/A N/A N/A N/A 1.134±0.00 N/A N/A 0.582±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007D2 CIL_0007D2_0001 CGP 9:19507452-20622543
CIL_0005UZ CIL_0005UZ_0002 CGP 9:20341665-20995955

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007379 IEA segment specification
GO:0008023 IDA transcription elongation factor complex
GO:0009952 IEA anterior/posterior pattern specification
GO:0070062 IDA extracellular vesicular exosome
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:2000096 IGI positive regulation of Wnt signaling pathway, planar cell polarity pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006754 mllt3 myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog (Drosophila) protein_coding Danio_rerio
ENSMUSG00000028496 Mllt3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 protein_coding Mus_musculus

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