C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Janus kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028530 Jak1 10090 - 4:101152367-101265282 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000102781 Jak1-001 101152367-101265282 protein_coding
  ENSMUST00000125968 Jak1-004 101197838-101265226 processed_transcript
  ENSMUST00000132292 Jak1-005 101181912-101265223 processed_transcript
  ENSMUST00000136167 Jak1-003 101179591-101185425 processed_transcript
  ENSMUST00000147211 Jak1-002 101181019-101185450 processed_transcript
  ENSMUST00000149297 Jak1-006 101191626-101265273 protein_coding
  ENSMUST00000151235 Jak1-008 101154249-101155119 processed_transcript
  ENSMUST00000155328 Jak1-007 101181872-101265281 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000102781ENSMUST00000149297ENSMUST00000155328
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000102781 41.451±9.65 27.307±2.82 20.853±0.97 16.116±2.14 44.730±8.15 24.934±2.06 19.151±0.61 26.355±0.78 15.858±2.77 38.412±1.20 26.560±5.00 58.481±7.81 21.076±7.14 7.273±0.40
ENSMUST00000149297 N/A 38.821±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000155328 N/A 23.564±3.89 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000268 CIL_000268_0002 CGP 4:101068983-101265282
CIL_000269 CIL_000269_0002 CGP 4:101152367-101466995

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004713 IDA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005131 IEA growth hormone receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005925 IEA focal adhesion
GO:0007167 IDA enzyme linked receptor protein signaling pathway
GO:0016020 IEA membrane
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019903 IEA protein phosphatase binding
GO:0031730 IEA CCR5 chemokine receptor binding
GO:0035556 IDA intracellular signal transduction
GO:0038110 IEA interleukin-2-mediated signaling pathway
GO:0046677 ISO response to antibiotic
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020625 jak1 Janus kinase 1 protein_coding Danio_rerio
ENSG00000162434 JAK1 Janus kinase 1 protein_coding Homo_sapiens

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