C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Janus kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162434 JAK1 9606 - 1:64833229-64966504 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342505 JAK1-001 64833229-64966504 protein_coding
  ENST00000465376 JAK1-006 64841474-64848107 processed_transcript
  ENST00000467764 JAK1-003 64875985-64879063 processed_transcript
  ENST00000471473 JAK1-005 64844096-64846909 processed_transcript
  ENST00000481702 JAK1-002 64839496-64841258 processed_transcript
  ENST00000494904 JAK1-004 64859642-64864856 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000342505
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000342505 49.588±0.00 26.708±0.00 5.700±0.00 10.164±3.11 19.008±8.78 16.207±9.65 16.615±9.03 19.308±4.81 13.320±6.29 34.351±8.89 19.748±11.79 17.262±8.01 21.246±1.53 27.142±3.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000268 CIL_000268_0001 CGP 1:64745095-64966504
CIL_000269 CIL_000269_0001 CGP 1:64833229-65232145

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005131 ISS growth hormone receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005925 IDA focal adhesion
GO:0006468 TAS:IEA protein phosphorylation
GO:0007167 IEA enzyme linked receptor protein signaling pathway
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019903 IPI protein phosphatase binding
GO:0031730 IEA CCR5 chemokine receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0038110 IDA interleukin-2-mediated signaling pathway
GO:0046677 IDA response to antibiotic
GO:0046777 IEA protein autophosphorylation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060334 TAS regulation of interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0060338 TAS regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020625 jak1 Janus kinase 1 protein_coding Danio_rerio
ENSMUSG00000028530 Jak1 Janus kinase 1 protein_coding Mus_musculus

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