C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, zeta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029053 Prkcz 10090 - 4:155260129-155361361 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030922 Prkcz-001 155261721-155361361 protein_coding
  ENSMUST00000103178 Prkcz-002 155260129-155345772 protein_coding
  ENSMUST00000105624 Prkcz-003 155356134-155361340 protein_coding
  ENSMUST00000123652 Prkcz-004 155290502-155345382 protein_coding
  ENSMUST00000125320 Prkcz-008 155294278-155301171 processed_transcript
  ENSMUST00000131975 Prkcz-006 155290502-155345165 protein_coding
  ENSMUST00000135699 Prkcz-009 155271133-155273042 processed_transcript
  ENSMUST00000139647 Prkcz-005 155290505-155345262 processed_transcript
  ENSMUST00000140256 Prkcz-010 155262100-155268335 processed_transcript
  ENSMUST00000145373 Prkcz-007 155294353-155344740 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030922ENSMUST00000103178ENSMUST00000105624ENSMUST00000125320ENSMUST00000140256
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030922 2.323±0.92 0.927±0.17 4.602±0.87 36.659±0.00 2.185±0.56 15.611±6.39 0.864±0.07 24.211±4.52 2.048±1.12 12.137±2.60 0.420±0.18 3.228±0.67 18.332±1.94 4.514±2.64
ENSMUST00000103178 0.576±0.24 0.361±0.00 0.555±0.00 17.028±3.28 N/A 7.076±0.00 0.162±0.00 N/A 0.135±0.00 N/A 0.077±0.02 0.723±0.00 2.289±0.33 N/A
ENSMUST00000105624 N/A 3.123±0.44 N/A N/A 4.403±0.91 N/A N/A N/A N/A N/A N/A 6.948±2.27 N/A N/A
ENSMUST00000125320 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 31.792±0.00
ENSMUST00000140256 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.311±0.00 N/A 12.020±0.67 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QV CIL_0007QV_0002 VISTA 4:154934679-155536167

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000226 IMP microtubule cytoskeleton organization
GO:0001954 IEA positive regulation of cell-matrix adhesion
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005815 IGI microtubule organizing center
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 ISS cell-cell junction
GO:0005923 IDA tight junction
GO:0005938 IDA cell cortex
GO:0006468 IDA protein phosphorylation
GO:0006954 IEA inflammatory response
GO:0007165 IEA signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007616 IEA long-term memory
GO:0008270 IEA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008286 IEA insulin receptor signaling pathway
GO:0015459 IEA potassium channel regulator activity
GO:0016324 IDA apical plasma membrane
GO:0016363 IDA nuclear matrix
GO:0016477 IEA cell migration
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030010 ISS establishment of cell polarity
GO:0031252 IEA cell leading edge
GO:0031333 IEA negative regulation of protein complex assembly
GO:0031532 IEA actin cytoskeleton reorganization
GO:0031584 IEA activation of phospholipase D activity
GO:0031941 IEA filamentous actin
GO:0032148 IEA activation of protein kinase B activity
GO:0032753 IMP positive regulation of interleukin-4 production
GO:0032869 IEA cellular response to insulin stimulus
GO:0034613 IEA cellular protein localization
GO:0035556 IEA intracellular signal transduction
GO:0035748 IDA myelin sheath abaxonal region
GO:0043066 IEA negative regulation of apoptotic process
GO:0043203 IDA axon hillock
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IDA protein complex
GO:0043274 IEA phospholipase binding
GO:0045121 IEA membrane raft
GO:0045179 IDA apical cortex
GO:0045630 IMP positive regulation of T-helper 2 cell differentiation
GO:0046326 IEA positive regulation of glucose import
GO:0046627 IEA negative regulation of insulin receptor signaling pathway
GO:0046628 ISS positive regulation of insulin receptor signaling pathway
GO:0046872 IEA metal ion binding
GO:0047496 IEA vesicle transport along microtubule
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050732 IEA negative regulation of peptidyl-tyrosine phosphorylation
GO:0050806 IEA positive regulation of synaptic transmission
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051222 IEA positive regulation of protein transport
GO:0051291 IEA protein heterooligomerization
GO:0051346 IEA negative regulation of hydrolase activity
GO:0051899 IEA membrane depolarization
GO:0060081 IEA membrane hyperpolarization
GO:0060291 ISS long-term synaptic potentiation
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070528 IEA protein kinase C signaling
GO:0071889 IEA 14-3-3 protein binding
GO:0072659 IMP protein localization to plasma membrane
GO:1990138 IGI neuron projection extension
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential
GO:2000553 IMP positive regulation of T-helper 2 cell cytokine production
GO:2000664 IMP positive regulation of interleukin-5 secretion
GO:2000667 IMP positive regulation of interleukin-13 secretion
GO:2001181 IMP positive regulation of interleukin-10 secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043332 prkcz protein kinase C, zeta protein_coding Danio_rerio
ENSG00000067606 PRKCZ protein kinase C, zeta protein_coding Homo_sapiens

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