C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase C, zeta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000030922 Prkcz-001 ENSMUSG00000029053 10090 - 4:155261721-155361361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030922
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030922 2.323±0.92 0.927±0.17 4.602±0.87 36.659±0.00 2.185±0.56 15.611±6.39 0.864±0.07 24.211±4.52 2.048±1.12 12.137±2.60 0.420±0.18 3.228±0.67 18.332±1.94 4.514±2.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QV CIL_0007QV_0002 VISTA 4:154934679-155536167

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000226 IMP microtubule cytoskeleton organization
GO:0001954 IEA positive regulation of cell-matrix adhesion
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005815 IGI microtubule organizing center
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 ISS cell-cell junction
GO:0005923 IDA tight junction
GO:0005938 IDA cell cortex
GO:0006468 IDA protein phosphorylation
GO:0006954 IEA inflammatory response
GO:0007165 IEA signal transduction
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007616 IEA long-term memory
GO:0008270 IEA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0008286 IEA insulin receptor signaling pathway
GO:0015459 IEA potassium channel regulator activity
GO:0016324 IDA apical plasma membrane
GO:0016363 IDA nuclear matrix
GO:0016477 IEA cell migration
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0019904 IEA protein domain specific binding
GO:0030010 ISS establishment of cell polarity
GO:0031252 IEA cell leading edge
GO:0031333 IEA negative regulation of protein complex assembly
GO:0031532 IEA actin cytoskeleton reorganization
GO:0031584 IEA activation of phospholipase D activity
GO:0031941 IEA filamentous actin
GO:0032148 IEA activation of protein kinase B activity
GO:0032753 IMP positive regulation of interleukin-4 production
GO:0032869 IEA cellular response to insulin stimulus
GO:0034613 IEA cellular protein localization
GO:0035748 IDA myelin sheath abaxonal region
GO:0043066 IEA negative regulation of apoptotic process
GO:0043203 IDA axon hillock
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IDA protein complex
GO:0043274 IEA phospholipase binding
GO:0045121 IEA membrane raft
GO:0045179 IDA apical cortex
GO:0045630 IMP positive regulation of T-helper 2 cell differentiation
GO:0046326 IEA positive regulation of glucose import
GO:0046627 IEA negative regulation of insulin receptor signaling pathway
GO:0046628 ISS positive regulation of insulin receptor signaling pathway
GO:0047496 IEA vesicle transport along microtubule
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050732 IEA negative regulation of peptidyl-tyrosine phosphorylation
GO:0050806 IEA positive regulation of synaptic transmission
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051222 IEA positive regulation of protein transport
GO:0051291 IEA protein heterooligomerization
GO:0051346 IEA negative regulation of hydrolase activity
GO:0051899 IEA membrane depolarization
GO:0060081 IEA membrane hyperpolarization
GO:0060291 ISS long-term synaptic potentiation
GO:0070062 IEA extracellular vesicular exosome
GO:0070374 ISS positive regulation of ERK1 and ERK2 cascade
GO:0070528 IEA protein kinase C signaling
GO:0071889 IEA 14-3-3 protein binding
GO:0072659 IMP protein localization to plasma membrane
GO:1990138 IGI neuron projection extension
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential
GO:2000553 IMP positive regulation of T-helper 2 cell cytokine production
GO:2000664 IMP positive regulation of interleukin-5 secretion
GO:2000667 IMP positive regulation of interleukin-13 secretion
GO:2001181 IMP positive regulation of interleukin-10 secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000063592 prkcz-001 protein_coding Danio_rerio 0 856
ENST00000378567 PRKCZ-001 protein_coding Homo_sapiens 0 2375
ENST00000392722 RP3-514P16.1-001 processed_pseudogene Homo_sapiens 0 283
ENST00000400920 PRKCZ-201 protein_coding Homo_sapiens 0 1936
ENST00000400921 PRKCZ-009 protein_coding Homo_sapiens 0 1934
ENST00000419838 PRKCZ-027 processed_transcript Homo_sapiens 0 327
ENST00000461106 PRKCZ-015 protein_coding Homo_sapiens 0 1893
ENST00000461465 PRKCZ-016 protein_coding Homo_sapiens 0 525
ENST00000466352 PRKCZ-006 protein_coding Homo_sapiens 0 414
ENST00000466651 PRKCZ-014 processed_transcript Homo_sapiens 0 300
ENST00000468310 PRKCZ-007 protein_coding Homo_sapiens 0 479
ENST00000470511 PRKCZ-021 protein_coding Homo_sapiens 0 599
ENST00000470596 PRKCZ-017 protein_coding Homo_sapiens 0 664
ENST00000470986 PRKCZ-010 protein_coding Homo_sapiens 0 688
ENST00000471018 PRKCZ-004 protein_coding Homo_sapiens 0 460
ENST00000472017 PRKCZ-023 processed_transcript Homo_sapiens 0 350
ENST00000478770 PRKCZ-012 nonsense_mediated_decay Homo_sapiens 0 1247
ENST00000479263 PRKCZ-002 processed_transcript Homo_sapiens 0 1615
ENST00000481140 PRKCZ-019 nonsense_mediated_decay Homo_sapiens 0 649
ENST00000482686 PRKCZ-003 protein_coding Homo_sapiens 0 566
ENST00000486681 PRKCZ-022 protein_coding Homo_sapiens 0 492
ENST00000495347 PRKCZ-020 protein_coding Homo_sapiens 0 409
ENST00000496325 PRKCZ-018 protein_coding Homo_sapiens 0 558
ENST00000497183 PRKCZ-011 protein_coding Homo_sapiens 0 368
ENST00000503672 PRKCZ-024 retained_intron Homo_sapiens 0 496
ENST00000505322 PRKCZ-025 retained_intron Homo_sapiens 0 1125

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