C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin carboxy-terminal hydrolase L1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029223 Uchl1 10090 + 5:66676098-66687231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031131 Uchl1-001 66676098-66687231 protein_coding
  ENSMUST00000176015 Uchl1-002 66676893-66687229 retained_intron
  ENSMUST00000177194 Uchl1-003 66676243-66676845 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031131ENSMUST00000176015ENSMUST00000177194
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031131 3.570±0.82 49.621±20.93 178.322±41.54 303.441±67.87 1.467±0.55 16.086±3.11 3.497±1.24 5.780±1.35 0.979±0.22 2.153±0.68 2.095±0.88 55.690±32.60 2.433±1.27 20.368±7.99
ENSMUST00000176015 1.818±0.73 8.793±0.43 112.535±38.13 207.039±54.64 1.428±0.58 8.322±2.67 3.271±0.56 2.654±1.41 0.709±0.70 2.395±0.54 1.155±0.60 44.776±18.27 2.378±1.70 14.871±6.11
ENSMUST00000177194 N/A N/A N/A N/A 0.869±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 4.588±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038S CIL_00038S_0002 CGP 5:66298861-66687231
CIL_00038J CIL_00038J_0002 CGP 5:66676098-67057159

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002931 IMP response to ischemia
GO:0004197 ISS cysteine-type endopeptidase activity
GO:0004221 IDA ubiquitin thiolesterase activity
GO:0004843 IEA ubiquitin-specific protease activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0007409 IMP axonogenesis
GO:0007412 IMP axon target recognition
GO:0007628 IGI adult walking behavior
GO:0008242 ISS omega peptidase activity
GO:0008283 IMP cell proliferation
GO:0016579 ISS protein deubiquitination
GO:0016874 IEA ligase activity
GO:0019233 IEA sensory perception of pain
GO:0019896 IMP axon transport of mitochondrion
GO:0030424 IDA axon
GO:0031694 IEA alpha-2A adrenergic receptor binding
GO:0042755 IGI eating behavior
GO:0043025 IDA neuronal cell body
GO:0043130 ISS ubiquitin binding
GO:0043407 IEA negative regulation of MAP kinase activity
GO:0048747 IGI muscle fiber development
GO:0050905 IMP neuromuscular process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026871 uchl1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) protein_coding Danio_rerio
ENSG00000154277 UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) protein_coding Homo_sapiens

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