C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM-domain containing, protein kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029674 Limk1 10090 - 5:134656039-134688590 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015137 Limk1-001 134656039-134688590 protein_coding
  ENSMUST00000111233 Limk1-002 134656040-134678248 protein_coding
  ENSMUST00000132027 Limk1-003 134668173-134688574 retained_intron
  ENSMUST00000134093 Limk1-004 134656199-134678220 nonsense_mediated_decay
  ENSMUST00000137897 Limk1-005 134663944-134668419 retained_intron
  ENSMUST00000138590 Limk1-006 134659994-134664205 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015137ENSMUST00000111233ENSMUST00000132027ENSMUST00000134093ENSMUST00000137897
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015137 4.650±1.44 9.237±4.76 3.766±0.08 19.023±1.79 2.747±1.30 1.282±0.46 1.109±0.22 1.373±0.41 0.605±0.35 4.969±0.36 0.401±0.18 3.370±1.43 20.852±11.38 6.240±2.35
ENSMUST00000111233 2.894±0.93 7.145±2.95 1.456±0.23 N/A 6.236±2.94 2.328±0.95 1.535±0.75 1.427±0.62 0.793±0.46 6.190±1.04 0.448±0.18 4.015±1.45 20.716±18.29 N/A
ENSMUST00000132027 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.555±0.00 N/A N/A
ENSMUST00000134093 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.157±0.00 N/A N/A N/A
ENSMUST00000137897 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.074±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005925 IDA focal adhesion
GO:0006468 ISS protein phosphorylation
GO:0008270 IEA zinc ion binding
GO:0031072 IEA heat shock protein binding
GO:0032233 IEA positive regulation of actin filament bundle assembly
GO:0043005 IDA neuron projection
GO:0045773 IGI positive regulation of axon extension
GO:0046982 IPI protein heterodimerization activity
GO:0051444 IEA negative regulation of ubiquitin-protein transferase activity
GO:0051496 IGI positive regulation of stress fiber assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003022 limk1b LIM domain kinase 1b protein_coding Danio_rerio
ENSDARG00000063651 limk1a LIM domain kinase 1a protein_coding Danio_rerio
ENSG00000106683 LIMK1 LIM domain kinase 1 protein_coding Homo_sapiens

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