C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ret proto-oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030110 Ret 10090 - 6:118151748-118197744 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032201 Ret-201 118151748-118197744 protein_coding
  ENSMUST00000088790 Ret-202 118151748-118197744 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032201ENSMUST00000088790
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032201 1.332±1.08 0.416±0.11 0.141±0.02 0.620±0.00 0.463±0.09 1.210±0.28 0.350±0.09 0.097±0.04 0.011±0.01 N/A 0.231±0.08 1.158±0.58 0.103±0.07 0.064±0.03
ENSMUST00000088790 4.394±3.02 0.333±0.15 0.516±0.04 1.532±0.74 0.675±0.20 1.803±0.21 0.796±0.19 0.164±0.03 0.023±0.02 0.524±0.04 0.541±0.12 0.905±0.48 0.183±0.12 0.196±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000338 CIL_000338_0002 CGP 6:118107452-118197744

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IGI MAPK cascade
GO:0001657 IMP ureteric bud development
GO:0001755 IMP neural crest cell migration
GO:0001838 IDA embryonic epithelial tube formation
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 IEA integral component of plasma membrane
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007158 IDA neuron cell-cell adhesion
GO:0007169 IGI transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 IMP nervous system development
GO:0009653 TAS anatomical structure morphogenesis
GO:0010008 IEA endosome membrane
GO:0010976 IEA positive regulation of neuron projection development
GO:0014042 IEA positive regulation of neuron maturation
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030155 IEA regulation of cell adhesion
GO:0030182 IMP neuron differentiation
GO:0030335 IEA positive regulation of cell migration
GO:0033619 IEA membrane protein proteolysis
GO:0033630 IEA positive regulation of cell adhesion mediated by integrin
GO:0035799 IMP ureter maturation
GO:0042493 IEA response to drug
GO:0042551 IMP neuron maturation
GO:0043235 ISO receptor complex
GO:0045121 IEA membrane raft
GO:0045793 IMP positive regulation of cell size
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0048265 IMP response to pain
GO:0048484 IMP enteric nervous system development
GO:0050770 IMP regulation of axonogenesis
GO:0060041 IEA retina development in camera-type eye
GO:0060384 IEA innervation
GO:0061146 IMP Peyer's patch morphogenesis
GO:0071300 IEA cellular response to retinoic acid
GO:0072300 IMP positive regulation of metanephric glomerulus development
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055305 ret ret proto-oncogene receptor tyrosine kinase protein_coding Danio_rerio
ENSG00000165731 RET ret proto-oncogene protein_coding Homo_sapiens

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