C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol 1,4,5-triphosphate receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030287 Itpr2 10090 - 6:146108299-146502223 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053273 Itpr2-002 146108299-146502099 protein_coding
  ENSMUST00000079573 Itpr2-001 146108299-146502178 protein_coding
  ENSMUST00000111673 Itpr2-003 146421418-146501878 processed_transcript
  ENSMUST00000131890 Itpr2-006 146357700-146396986 protein_coding
  ENSMUST00000137938 Itpr2-007 146120595-146147208 processed_transcript
  ENSMUST00000139732 Itpr2-004 146373123-146502223 protein_coding
  ENSMUST00000144557 Itpr2-009 146290486-146294284 processed_transcript
  ENSMUST00000145418 Itpr2-005 146382134-146502178 retained_intron
  ENSMUST00000155339 Itpr2-008 146180336-146196960 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053273ENSMUST00000079573ENSMUST00000131890
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053273 1.509±0.07 1.229±0.11 0.614±0.02 0.442±0.46 2.388±0.84 1.291±0.40 1.176±0.58 3.620±1.21 0.845±0.68 2.397±0.66 0.435±0.15 4.201±2.65 1.807±1.90 0.527±0.27
ENSMUST00000079573 3.980±1.76 1.965±0.19 0.282±0.00 0.213±0.00 2.511±1.23 1.546±0.32 0.537±0.33 6.907±2.78 0.796±0.58 5.772±1.15 0.215±0.01 4.033±1.83 0.412±0.17 0.551±0.00
ENSMUST00000131890 N/A 3.763±0.00 N/A N/A 3.027±0.00 1.746±0.00 N/A N/A N/A N/A N/A 7.214±0.36 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004XE CIL_0004XE_0002 CGP 6:145931641-146502223
CIL_0004XF CIL_0004XF_0002 CGP 6:146108299-146577835

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0005220 IDA inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005938 IDA cell cortex
GO:0006816 IDA calcium ion transport
GO:0015278 IDA calcium-release channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0033017 IEA sarcoplasmic reticulum membrane
GO:0035091 IDA phosphatidylinositol binding
GO:0043235 ISO receptor complex
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0070588 IEA calcium ion transmembrane transport
GO:0071320 IDA cellular response to cAMP
GO:0071361 IMP cellular response to ethanol

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011909 itpr2 inositol 1,4,5-triphosphate receptor, type 2 protein_coding Danio_rerio
ENSG00000123104 ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 protein_coding Homo_sapiens

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