C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol 1,4,5-triphosphate receptor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000053273 Itpr2-002 ENSMUSG00000030287 10090 - 6:146108299-146502099 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053273
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053273 1.509±0.07 1.229±0.11 0.614±0.02 0.442±0.46 2.388±0.84 1.291±0.40 1.176±0.58 3.620±1.21 0.845±0.68 2.397±0.66 0.435±0.15 4.201±2.65 1.807±1.90 0.527±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004XE CIL_0004XE_0002 CGP 6:145931641-146502223
CIL_0004XF CIL_0004XF_0002 CGP 6:146108299-146577835

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0005220 IDA inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0005938 IDA cell cortex
GO:0006816 IDA calcium ion transport
GO:0015278 IDA calcium-release channel activity
GO:0016021 IEA integral component of membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0033017 IEA sarcoplasmic reticulum membrane
GO:0035091 IDA phosphatidylinositol binding
GO:0043235 ISO receptor complex
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0070588 IEA calcium ion transmembrane transport
GO:0071320 IDA cellular response to cAMP
GO:0071361 IMP cellular response to ethanol

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000242737 ITPR2-002 protein_coding Homo_sapiens 0 638
ENST00000374316 ITPR3-001 protein_coding Homo_sapiens 0 416
ENST00000381340 ITPR2-001 protein_coding Homo_sapiens 0 8456
ENST00000451599 ITPR2-004 nonsense_mediated_decay Homo_sapiens 0 2176
ENST00000540791 ITPR2-010 processed_transcript Homo_sapiens 0 385
ENST00000545235 ITPR2-003 nonsense_mediated_decay Homo_sapiens 3e-35 152
ENST00000605930 ITPR3-201 protein_coding Homo_sapiens 0 416

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