C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: autophagy related 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030314 Atg7 10090 + 6:114643097-114860614 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032457 Atg7-001 114643097-114860614 protein_coding
  ENSMUST00000169310 Atg7-006 114643112-114860612 protein_coding
  ENSMUST00000182034 Atg7-009 114652436-114686202 protein_coding
  ENSMUST00000182035 Atg7-011 114643131-114686219 protein_coding
  ENSMUST00000182098 Atg7-007 114643127-114673115 protein_coding
  ENSMUST00000182169 Atg7-012 114643118-114677998 protein_coding
  ENSMUST00000182428 Atg7-003 114643129-114859230 protein_coding
  ENSMUST00000182510 Atg7-008 114648846-114684517 protein_coding
  ENSMUST00000182771 Atg7-010 114658064-114673696 protein_coding
  ENSMUST00000182793 Atg7-004 114643127-114859221 protein_coding
  ENSMUST00000182860 Atg7-014 114723100-114859224 processed_transcript
  ENSMUST00000182902 Atg7-005 114643129-114859224 protein_coding
  ENSMUST00000182934 Atg7-015 114856151-114859222 processed_transcript
  ENSMUST00000183127 Atg7-013 114643116-114684913 retained_intron
  ENSMUST00000183165 Atg7-002 114643122-114859130 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032457ENSMUST00000169310ENSMUST00000182428ENSMUST00000182793ENSMUST00000182860ENSMUST00000182902ENSMUST00000183165
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032457 12.766±3.25 6.641±2.90 8.405±0.64 5.875±1.08 8.215±4.29 7.353±2.56 3.114±0.67 7.068±1.76 6.796±3.80 11.097±2.54 1.875±0.82 7.343±2.16 5.968±2.10 4.695±1.99
ENSMUST00000169310 N/A N/A N/A N/A N/A N/A 1.184±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000182428 N/A N/A N/A 4.547±0.00 N/A N/A N/A N/A 1.689±0.29 N/A N/A N/A 4.845±0.00 5.774±1.37
ENSMUST00000182793 7.141±3.14 4.632±0.36 N/A N/A 4.208±1.04 4.421±0.71 1.057±0.00 2.962±0.03 5.582±3.39 4.427±0.00 N/A 3.761±0.24 1.955±0.00 12.428±4.49
ENSMUST00000182860 N/A 31.932±2.63 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000182902 N/A N/A N/A N/A N/A N/A 1.010±0.00 N/A N/A N/A N/A 3.976±0.00 N/A 3.635±0.00
ENSMUST00000183165 N/A N/A N/A N/A N/A 5.041±0.00 N/A N/A N/A N/A N/A 6.942±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00061H CIL_00061H_0002 CGP 6:114397936-114860614
CIL_0005SK CIL_0005SK_0002 CGP 6:114643097-114969994

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000407 IBA pre-autophagosomal structure
GO:0000422 IBA mitochondrion degradation
GO:0001889 IMP liver development
GO:0004839 IDA ubiquitin activating enzyme activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005829 IBA cytosol
GO:0005930 IDA axoneme
GO:0006497 ISO protein lipidation
GO:0006501 IBA C-terminal protein lipidation
GO:0006520 IMP cellular amino acid metabolic process
GO:0006914 IMP autophagy
GO:0006995 IBA cellular response to nitrogen starvation
GO:0006996 IMP organelle organization
GO:0007005 IMP mitochondrion organization
GO:0007628 IMP adult walking behavior
GO:0008134 IEA transcription factor binding
GO:0009267 ISS cellular response to starvation
GO:0009791 IMP post-embryonic development
GO:0010508 ISS positive regulation of autophagy
GO:0015031 IEA protein transport
GO:0016236 IBA macroautophagy
GO:0016239 IEA positive regulation of macroautophagy
GO:0016567 IDA protein ubiquitination
GO:0019778 IMP Atg12 activating enzyme activity
GO:0019779 IBA Atg8 activating enzyme
GO:0021680 IMP cerebellar Purkinje cell layer development
GO:0021860 IMP pyramidal neuron development
GO:0021955 IMP central nervous system neuron axonogenesis
GO:0021987 IMP cerebral cortex development
GO:0030163 IMP protein catabolic process
GO:0031175 IMP neuron projection development
GO:0031396 IMP regulation of protein ubiquitination
GO:0031401 IDA positive regulation of protein modification process
GO:0032446 IMP protein modification by small protein conjugation
GO:0034727 IBA piecemeal microautophagy of nucleus
GO:0039689 IMP negative stranded viral RNA replication
GO:0042594 IMP response to starvation
GO:0042803 IEA protein homodimerization activity
GO:0043065 ISS positive regulation of apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0044805 IBA late nucleophagy
GO:0045732 ISS positive regulation of protein catabolic process
GO:0050877 IMP neurological system process
GO:0055013 IMP cardiac muscle cell development
GO:0061024 IMP membrane organization
GO:0070257 IMP positive regulation of mucus secretion
GO:0071455 ISS cellular response to hyperoxia
GO:2000619 IMP negative regulation of histone H4-K16 acetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078008 ATG7 autophagy related 7 protein_coding Danio_rerio
ENSG00000197548 ATG7 autophagy related 7 protein_coding Homo_sapiens

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