C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030541 Idh2 10090 - 7:80094846-80115392 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000107384 Idh2-001 80094846-80115392 protein_coding
  ENSMUST00000125542 Idh2-003 80096028-80100881 processed_transcript
  ENSMUST00000134070 Idh2-004 80098166-80099139 retained_intron
  ENSMUST00000134328 Idh2-002 80094850-80115332 nonsense_mediated_decay
  ENSMUST00000139178 Idh2-005 80095029-80098409 retained_intron
  ENSMUST00000156761 Idh2-006 80095043-80096029 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107384ENSMUST00000134070ENSMUST00000139178ENSMUST00000156761
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107384 63.644±11.64 66.699±15.31 32.243±1.08 42.673±21.22 47.305±10.10 62.194±4.46 536.074±59.84 239.373±36.89 81.108±21.56 52.141±16.34 138.020±36.45 74.489±17.68 93.237±32.83 3.089±1.05
ENSMUST00000134070 N/A N/A N/A 21.461±3.30 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000139178 N/A N/A N/A 17.569±5.37 N/A N/A N/A N/A N/A 14.849±0.00 N/A 26.995±2.10 20.023±2.63 0.910±0.25
ENSMUST00000156761 N/A N/A N/A 37.995±0.00 N/A N/A N/A N/A N/A N/A N/A 108.972±0.00 143.755±46.38 6.615±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001T4 CIL_0001T4_0003 CGP 7:80024814-80115392
CIL_00079J CIL_00079J_0002 CGP 7:80094846-80226394

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004450 ISS isocitrate dehydrogenase (NADP+) activity
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0006097 IEA glyoxylate cycle
GO:0006099 IEA tricarboxylic acid cycle
GO:0006102 ISS isocitrate metabolic process
GO:0006103 ISS 2-oxoglutarate metabolic process
GO:0006950 IEA response to stress
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003795 IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial protein_coding Danio_rerio
ENSG00000182054 IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial protein_coding Homo_sapiens

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