C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107384 Idh2-001 ENSMUSG00000030541 10090 - 7:80094846-80115392 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107384
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107384 63.644±11.64 66.699±15.31 32.243±1.08 42.673±21.22 47.305±10.10 62.194±4.46 536.074±59.84 239.373±36.89 81.108±21.56 52.141±16.34 138.020±36.45 74.489±17.68 93.237±32.83 3.089±1.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001T4 CIL_0001T4_0003 CGP 7:80024814-80115392
CIL_00079J CIL_00079J_0002 CGP 7:80094846-80226394

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004450 ISS isocitrate dehydrogenase (NADP+) activity
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0006097 IEA glyoxylate cycle
GO:0006099 IEA tricarboxylic acid cycle
GO:0006102 ISS isocitrate metabolic process
GO:0006103 ISS 2-oxoglutarate metabolic process
GO:0006950 IEA response to stress
GO:0051287 IEA NAD binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000330062 IDH2-001 protein_coding Homo_sapiens 0 1892
ENST00000540499 IDH2-004 protein_coding Homo_sapiens 0 1650
ENST00000559482 IDH2-002 protein_coding Homo_sapiens 0 817
ENST00000560061 IDH2-003 nonsense_mediated_decay Homo_sapiens 0 1290

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