C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 2, group F, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030551 Nr2f2 10090 - 7:70351946-70366735 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032768 Nr2f2-001 70351946-70360593 protein_coding
  ENSMUST00000089565 Nr2f2-002 70354439-70366735 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032768ENSMUST00000089565
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032768 15.153±8.71 32.839±3.82 13.119±0.63 14.501±9.37 8.399±4.52 11.767±1.63 1.967±0.84 16.204±3.45 3.519±0.63 18.844±2.22 1.902±0.41 50.793±24.73 3.826±0.98 1.067±0.47
ENSMUST00000089565 22.169±17.33 56.235±0.80 24.305±5.88 17.916±12.77 5.512±1.31 N/A 3.339±0.53 20.722±3.57 3.635±1.44 18.229±0.98 1.269±0.17 25.108±12.79 8.761±7.42 2.200±0.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007O7 CIL_0007O7_0003 UCNEbase 7:69097096-72048391
CIL_000932 CIL_000932_0002 VISTA 7:69817148-70419432

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001701 IMP in utero embryonic development
GO:0001764 IDA neuron migration
GO:0001893 IMP maternal placenta development
GO:0001937 IEA negative regulation of endothelial cell proliferation
GO:0001945 IEP lymph vessel development
GO:0001972 ISS retinoic acid binding
GO:0003677 IDA DNA binding
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 ISS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007519 IMP skeletal muscle tissue development
GO:0008270 IEA zinc ion binding
GO:0009566 IMP fertilization
GO:0009952 IMP anterior/posterior pattern specification
GO:0009956 IMP radial pattern formation
GO:0010596 IEA negative regulation of endothelial cell migration
GO:0030522 IEA intracellular receptor signaling pathway
GO:0030900 IDA forebrain development
GO:0032355 IEA response to estradiol
GO:0042803 IEA protein homodimerization activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA sequence-specific DNA binding
GO:0045736 IEA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0048514 IMP blood vessel morphogenesis
GO:0060173 IMP limb development
GO:0060674 IMP placenta blood vessel development
GO:0060707 IMP trophoblast giant cell differentiation
GO:0060849 IEA regulation of transcription involved in lymphatic endothelial cell fate commitment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040926 nr2f2 nuclear receptor subfamily 2, group F, member 2 protein_coding Danio_rerio
ENSG00000185551 NR2F2 nuclear receptor subfamily 2, group F, member 2 protein_coding Homo_sapiens

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