C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 2, group F, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185551 NR2F2 9606 + 15:96325938-96340263 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000394166 NR2F2-001 96330717-96340263 protein_coding
  ENST00000394171 NR2F2-201 96332565-96340263 protein_coding
  ENST00000421109 NR2F2-002 96325938-96338618 protein_coding
  ENST00000453270 NR2F2-003 96333163-96337836 protein_coding
  ENST00000559679 NR2F2-004 96332537-96334372 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394166ENST00000421109ENST00000453270
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394166 18.878±0.00 20.084±0.00 7.017±0.00 1.192±0.96 4.415±3.51 11.543±0.00 1.929±1.79 9.162±7.94 1.994±0.71 9.091±7.22 2.652±2.48 21.959±20.59 7.060±3.52 11.965±9.90
ENST00000421109 21.112±0.00 35.457±0.00 N/A 1.631±0.48 10.111±2.14 13.320±9.64 0.401±0.00 15.073±11.59 3.890±1.25 3.269±0.00 0.796±0.00 27.871±21.14 22.616±9.30 28.806±18.06
ENST00000453270 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.984±0.00 7.485±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007O7 CIL_0007O7_0001 UCNEbase 15:94530989-96398057
CIL_000932 CIL_000932_0001 VISTA 15:96284824-96887064

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001701 IEA in utero embryonic development
GO:0001764 IEA neuron migration
GO:0001893 IEA maternal placenta development
GO:0001937 IMP negative regulation of endothelial cell proliferation
GO:0001945 IEA lymph vessel development
GO:0001972 IDA retinoic acid binding
GO:0003677 IEA DNA binding
GO:0003700 IC:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003714 TAS transcription corepressor activity
GO:0004879 IEA:IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006629 TAS lipid metabolic process
GO:0007165 TAS signal transduction
GO:0007519 IEA skeletal muscle tissue development
GO:0008270 IEA zinc ion binding
GO:0009566 IEA fertilization
GO:0009952 IEA anterior/posterior pattern specification
GO:0009956 IEA radial pattern formation
GO:0010596 IMP negative regulation of endothelial cell migration
GO:0030522 IEA intracellular receptor signaling pathway
GO:0030900 IEA forebrain development
GO:0032355 IEA response to estradiol
GO:0042803 IPI protein homodimerization activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA:IEA sequence-specific DNA binding
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048514 IEA blood vessel morphogenesis
GO:0060173 IEA limb development
GO:0060674 IEA placenta blood vessel development
GO:0060707 IEA trophoblast giant cell differentiation
GO:0060849 IMP regulation of transcription involved in lymphatic endothelial cell fate commitment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040926 nr2f2 nuclear receptor subfamily 2, group F, member 2 protein_coding Danio_rerio
ENSMUSG00000030551 Nr2f2 nuclear receptor subfamily 2, group F, member 2 protein_coding Mus_musculus

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