C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphodiesterase 2A, cGMP-stimulated
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030653 Pde2a 10090 + 7:101421691-101512829 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084894 Pde2a-201 101421691-101512829 protein_coding
  ENSMUST00000163751 Pde2a-202 101421691-101512829 protein_coding
  ENSMUST00000166652 Pde2a-203 101421709-101512814 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084894ENSMUST00000163751ENSMUST00000166652
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084894 9.529±7.13 14.132±3.90 3.985±0.00 18.208±17.54 6.596±0.41 9.088±0.00 4.134±0.80 4.930±2.54 1.527±0.49 3.370±0.00 2.071±0.00 5.742±1.76 4.118±4.26 1.246±0.23
ENSMUST00000163751 1.468±0.00 N/A N/A 4.837±4.83 N/A 3.526±0.00 1.753±0.00 1.213±0.03 N/A 0.717±0.00 1.476±0.30 1.402±0.68 N/A 0.532±0.00
ENSMUST00000166652 N/A N/A N/A 22.431±0.00 4.065±2.04 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XL CIL_0008XL_0002 VISTA 7:101413526-102014552

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0004112 IEA cyclic-nucleotide phosphodiesterase activity
GO:0004114 IEA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004118 IEA cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006198 IEA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0008144 IEA drug binding
GO:0008152 IEA metabolic process
GO:0019933 IEA cAMP-mediated signaling
GO:0019934 IEA cGMP-mediated signaling
GO:0030224 IEA monocyte differentiation
GO:0030424 IDA axon
GO:0030425 IDA dendrite
GO:0030552 IEA cAMP binding
GO:0030553 IEA cGMP binding
GO:0030823 IGI regulation of cGMP metabolic process
GO:0030911 IEA TPR domain binding
GO:0033159 IEA negative regulation of protein import into nucleus, translocation
GO:0035690 IEA cellular response to drug
GO:0036006 IEA cellular response to macrophage colony-stimulating factor stimulus
GO:0042803 IEA protein homodimerization activity
GO:0043116 IEA negative regulation of vascular permeability
GO:0043117 IEA positive regulation of vascular permeability
GO:0046069 IEA cGMP catabolic process
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0071321 IEA cellular response to cGMP
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:0097011 IEA cellular response to granulocyte macrophage colony-stimulating factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079064 PDE2A (1 of 2) phosphodiesterase 2A, cGMP-stimulated protein_coding Danio_rerio
ENSDARG00000091508 PDE2A (2 of 2) phosphodiesterase 2A, cGMP-stimulated protein_coding Danio_rerio
ENSG00000186642 PDE2A phosphodiesterase 2A, cGMP-stimulated protein_coding Homo_sapiens

Loading