C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphodiesterase 2A, cGMP-stimulated
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000163751 Pde2a-202 ENSMUSG00000030653 10090 + 7:101421691-101512829 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLungMuscleOvaryTestisENSMUST00000163751
Transcript ID Adipose Brain Colon Heart Kidney Lung Muscle Ovary Testis
ENSMUST00000163751 1.468±0.00 4.837±4.83 3.526±0.00 1.753±0.00 1.213±0.03 0.717±0.00 1.476±0.30 1.402±0.68 0.532±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XL CIL_0008XL_0002 VISTA 7:101413526-102014552

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0004112 IEA cyclic-nucleotide phosphodiesterase activity
GO:0004118 IEA cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006198 IEA cAMP catabolic process
GO:0008144 IEA drug binding
GO:0019933 IEA cAMP-mediated signaling
GO:0019934 IEA cGMP-mediated signaling
GO:0030224 IEA monocyte differentiation
GO:0030424 IDA axon
GO:0030425 IDA dendrite
GO:0030552 IEA cAMP binding
GO:0030553 IEA cGMP binding
GO:0030823 IGI regulation of cGMP metabolic process
GO:0030911 IEA TPR domain binding
GO:0033159 IEA negative regulation of protein import into nucleus, translocation
GO:0035690 IEA cellular response to drug
GO:0036006 IEA cellular response to macrophage colony-stimulating factor stimulus
GO:0042803 IEA protein homodimerization activity
GO:0043116 IEA negative regulation of vascular permeability
GO:0043117 IEA positive regulation of vascular permeability
GO:0046069 IEA cGMP catabolic process
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0071321 IEA cellular response to cGMP
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:0097011 IEA cellular response to granulocyte macrophage colony-stimulating factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000131089 PDE2A (2 of 2)-201 protein_coding Danio_rerio 0 311
ENST00000334456 PDE2A-001 protein_coding Homo_sapiens 0 3698
ENST00000376450 PDE2A-003 protein_coding Homo_sapiens 0 2492
ENST00000418754 PDE2A-010 protein_coding Homo_sapiens 0 2942
ENST00000420501 PDE2A-004 protein_coding Homo_sapiens 0 870
ENST00000441209 PDE2A-005 protein_coding Homo_sapiens 0 1118
ENST00000444035 PDE2A-201 protein_coding Homo_sapiens 0 3290
ENST00000475807 PDE2A-008 protein_coding Homo_sapiens 0 1046
ENST00000485058 PDE2A-007 processed_transcript Homo_sapiens 2e-22 110
ENST00000490749 PDE2A-006 retained_intron Homo_sapiens 2e-21 106
ENST00000535701 PDE2A-015 nonsense_mediated_decay Homo_sapiens 0 412
ENST00000536308 PDE2A-021 nonsense_mediated_decay Homo_sapiens 0 257
ENST00000536458 PDE2A-016 protein_coding Homo_sapiens 1e-18 97
ENST00000536918 PDE2A-027 retained_intron Homo_sapiens 0 555
ENST00000537631 PDE2A-020 nonsense_mediated_decay Homo_sapiens 0 294
ENST00000538299 PDE2A-024 protein_coding Homo_sapiens 0 553
ENST00000538749 PDE2A-017 protein_coding Homo_sapiens 0 339
ENST00000539367 PDE2A-002 nonsense_mediated_decay Homo_sapiens 0 2436
ENST00000540345 PDE2A-012 protein_coding Homo_sapiens 0 3314
ENST00000540380 PDE2A-013 processed_transcript Homo_sapiens 0 322
ENST00000541998 PDE2A-022 nonsense_mediated_decay Homo_sapiens 1e-17 97
ENST00000542223 PDE2A-025 protein_coding Homo_sapiens 0 797
ENST00000542969 PDE2A-009 protein_coding Homo_sapiens 0 416
ENST00000543575 PDE2A-023 nonsense_mediated_decay Homo_sapiens 1e-17 97
ENST00000543750 PDE2A-019 nonsense_mediated_decay Homo_sapiens 0 287
ENST00000544570 PDE2A-018 protein_coding Homo_sapiens 0 3367
ENST00000546038 PDE2A-014 nonsense_mediated_decay Homo_sapiens 0 320

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