C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear protein transcription regulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030717 Nupr1 10090 - 7:126623249-126630861 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032961 Nupr1-001 126623249-126625676 protein_coding
  ENSMUST00000131174 Nupr1-003 126623252-126627010 retained_intron
  ENSMUST00000151105 Nupr1-002 126624948-126626016 processed_transcript
  ENSMUST00000187609 Nupr1-006 126623442-126625475 processed_transcript
  ENSMUST00000191192 Nupr1-005 126623278-126625344 nonsense_mediated_decay
  ENSMUST00000191413 Nupr1-004 126624948-126630861 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032961ENSMUST00000131174ENSMUST00000151105ENSMUST00000187609ENSMUST00000191192ENSMUST00000191413
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032961 34.887±16.54 1.815±0.63 27.165±2.68 2.884±2.68 18.935±2.15 80.817±12.44 3.463±1.60 14.253±1.51 1.544±1.59 31.786±6.85 4.451±1.12 97.188±48.45 5.897±4.92 0.982±0.32
ENSMUST00000131174 2.496±0.11 0.635±0.23 1.365±0.00 0.058±0.00 6.321±1.86 9.071±1.53 0.507±0.18 0.934±0.30 0.199±0.13 3.455±0.79 N/A 7.320±1.36 0.067±0.01 0.075±0.03
ENSMUST00000151105 N/A N/A N/A N/A N/A N/A N/A N/A 0.283±0.11 N/A N/A N/A N/A N/A
ENSMUST00000187609 N/A N/A N/A N/A N/A N/A N/A N/A 0.263±0.12 N/A N/A 17.899±4.91 N/A N/A
ENSMUST00000191192 N/A N/A N/A 3.490±3.16 N/A N/A 1.143±0.00 N/A 0.960±0.72 N/A 2.189±0.73 130.722±33.35 5.052±3.00 2.488±0.00
ENSMUST00000191413 N/A N/A N/A 12.327±0.00 N/A N/A N/A N/A N/A N/A N/A 197.745±0.00 12.316±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005TU CIL_0005TU_0002 CGP 7:126589010-126630861
CIL_0004WL CIL_0004WL_0002 CGP 7:126623249-126672925

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002526 IMP acute inflammatory response
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006461 IMP protein complex assembly
GO:0006473 IMP protein acetylation
GO:0008584 IMP male gonad development
GO:0009636 IMP response to toxic substance
GO:0016049 IEA cell growth
GO:0031401 IMP positive regulation of protein modification process
GO:0035914 IMP skeletal muscle cell differentiation
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 IMP positive regulation of apoptotic process
GO:0045786 IMP negative regulation of cell cycle
GO:0048147 IMP negative regulation of fibroblast proliferation
GO:2000194 IMP regulation of female gonad development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094557 nupr1 nuclear protein 1 protein_coding Danio_rerio
ENSG00000176046 NUPR1 nuclear protein, transcriptional regulator, 1 protein_coding Homo_sapiens

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