C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000032974 Atp2a1-001 ENSMUSG00000030730 10090 - 7:126445858-126463108 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartKidneyLiverLungMusclePlacentaENSMUST00000032974
Transcript ID Breast Heart Kidney Liver Lung Muscle Placenta
ENSMUST00000032974 1102.983±258.54 1.086±0.36 38.458±1.00 0.797±0.00 21.915±19.61 7450.746±352.77 0.681±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000557 CIL_000557_0002 CGP 7:126428759-126463108

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005388 ISS calcium-transporting ATPase activity
GO:0005509 ISS calcium ion binding
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005783 ISS endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0005793 ISS endoplasmic reticulum-Golgi intermediate compartment
GO:0006200 ISS ATP catabolic process
GO:0006816 ISS calcium ion transport
GO:0006937 TAS regulation of muscle contraction
GO:0006942 ISS regulation of striated muscle contraction
GO:0008637 IEA apoptotic mitochondrial changes
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0016529 ISS sarcoplasmic reticulum
GO:0031448 ISS positive regulation of fast-twitch skeletal muscle fiber contraction
GO:0031673 ISS H zone
GO:0031674 ISS I band
GO:0032470 IEA positive regulation of endoplasmic reticulum calcium ion concentration
GO:0032471 IEA negative regulation of endoplasmic reticulum calcium ion concentration
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0042803 IEA protein homodimerization activity
GO:0045988 ISS negative regulation of striated muscle contraction
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051561 IEA positive regulation of mitochondrial calcium ion concentration
GO:0051659 IEA maintenance of mitochondrion location
GO:0070059 IEA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070509 IEA calcium ion import
GO:0090076 IEA relaxation of skeletal muscle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000146241 atp2a2a-003 protein_coding Danio_rerio 0 1773
ENSDART00000042040 atp2a2a-001 protein_coding Danio_rerio 0 1773
ENSDART00000043932 atp2a1-001 protein_coding Danio_rerio 0 1738
ENSDART00000129561 atp2a1-002 protein_coding Danio_rerio 0 1738
ENSDART00000047201 atp2a2b-001 protein_coding Danio_rerio 0 1616
ENSDART00000105896 atp2a1l-001 protein_coding Danio_rerio 0 1550
ENSDART00000133432 atp2a3-001 protein_coding Danio_rerio 0 1343
ENSDART00000086443 atp2a3-201 protein_coding Danio_rerio 0 1253
ENSDART00000133210 si:dkey-28b4.8-001 protein_coding Danio_rerio 0 634
ENSDART00000046562 si:dkey-28b4.8-201 protein_coding Danio_rerio 0 617
ENST00000309890 ATP2A3-201 protein_coding Homo_sapiens 0 1411
ENST00000352011 ATP2A3-015 protein_coding Homo_sapiens 0 1411
ENST00000357084 ATP2A1-001 protein_coding Homo_sapiens 0 3923
ENST00000359983 ATP2A3-005 protein_coding Homo_sapiens 0 1411
ENST00000395503 ATP2A1-002 protein_coding Homo_sapiens 0 4098
ENST00000397035 ATP2A3-004 protein_coding Homo_sapiens 0 1411
ENST00000397041 ATP2A3-001 protein_coding Homo_sapiens 0 1411
ENST00000397043 ATP2A3-002 protein_coding Homo_sapiens 0 1411
ENST00000536376 ATP2A1-003 protein_coding Homo_sapiens 0 3720
ENST00000562185 ATP2A1-008 protein_coding Homo_sapiens 0 409
ENST00000564732 ATP2A1-009 nonsense_mediated_decay Homo_sapiens 0 612
ENST00000576957 ATP2A3-012 retained_intron Homo_sapiens 0 291

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