C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ornithine transcarbamylase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031173 Otc 10090 + X:10252305-10321024 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049910 Otc-001 10252305-10321024 protein_coding
  ENSMUST00000115528 Otc-002 10252367-10316864 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaENSMUST00000049910ENSMUST00000115528
Transcript ID Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta
ENSMUST00000049910 0.005±0.00 0.008±0.00 0.334±0.18 2.077±0.41 0.025±0.01 59.011±61.56 0.146±0.08 0.030±0.01 0.098±0.05 0.530±0.62
ENSMUST00000115528 N/A N/A N/A N/A N/A N/A N/A N/A 0.040±0.03 0.048±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005YY CIL_0005YY_0002 CGP X:10073621-10321024
CIL_0005QH CIL_0005QH_0002 CGP X:10252305-10596605

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000050 IEA urea cycle
GO:0001889 IEA liver development
GO:0004585 IEA ornithine carbamoyltransferase activity
GO:0005543 IEA phospholipid binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0006520 IEA cellular amino acid metabolic process
GO:0006526 IEA arginine biosynthetic process
GO:0006591 IEA ornithine metabolic process
GO:0006593 IEA ornithine catabolic process
GO:0007494 IEA midgut development
GO:0010043 IEA response to zinc ion
GO:0016597 IEA amino acid binding
GO:0016743 IEA carboxyl- or carbamoyltransferase activity
GO:0019240 IEA citrulline biosynthetic process
GO:0031667 IEA response to nutrient levels
GO:0032868 IEA response to insulin
GO:0042301 IEA phosphate ion binding
GO:0042493 IEA response to drug
GO:0055081 IEA anion homeostasis
GO:0070207 IEA protein homotrimerization
GO:0070781 IEA response to biotin
GO:0097272 IEA ammonia homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062147 otc ornithine carbamoyltransferase protein_coding Danio_rerio
ENSG00000036473 OTC ornithine carbamoyltransferase protein_coding Homo_sapiens

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