C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuroligin 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031302 Nlgn3 10090 + X:101299168-101325963 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065858 Nlgn3-001 101299210-101325963 protein_coding
  ENSMUST00000118111 Nlgn3-002 101299168-101325963 protein_coding
  ENSMUST00000130555 Nlgn3-003 101299175-101318675 protein_coding
  ENSMUST00000144860 Nlgn3-007 101314391-101318151 processed_transcript
  ENSMUST00000147443 Nlgn3-006 101300474-101302054 processed_transcript
  ENSMUST00000151528 Nlgn3-004 101299194-101325963 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENSMUST00000065858ENSMUST00000118111
Transcript ID Brain
ENSMUST00000065858 8.842±5.30
ENSMUST00000118111 5.219±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00057X CIL_00057X_0002 CGP X:101274030-101325963
CIL_00057N CIL_00057N_0002 CGP X:101299168-101385629

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002087 IGI regulation of respiratory gaseous exchange by neurological system process
GO:0004872 IBA receptor activity
GO:0005515 IEA protein binding
GO:0005887 IBA:ISS integral component of plasma membrane
GO:0006898 ISS receptor-mediated endocytosis
GO:0007155 IEA cell adhesion
GO:0007158 ISS neuron cell-cell adhesion
GO:0007416 IBA synapse assembly
GO:0007612 IEA learning
GO:0008542 IMP visual learning
GO:0009986 IBA:ISS cell surface
GO:0030054 IEA cell junction
GO:0030139 ISS endocytic vesicle
GO:0030534 IEA adult behavior
GO:0035176 IMP social behavior
GO:0042043 IBA:ISS neurexin family protein binding
GO:0045202 IBA synapse
GO:0048675 ISS axon extension
GO:0048709 IMP oligodendrocyte differentiation
GO:0050804 IGI regulation of synaptic transmission
GO:0050808 ISO synapse organization
GO:0050839 ISS cell adhesion molecule binding
GO:0051965 ISS positive regulation of synapse assembly
GO:0051966 IMP regulation of synaptic transmission, glutamatergic
GO:0051968 IMP positive regulation of synaptic transmission, glutamatergic
GO:0060024 ISS rhythmic synaptic transmission
GO:0060076 ISS excitatory synapse
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0060080 IMP regulation of inhibitory postsynaptic membrane potential
GO:0061001 IMP regulation of dendritic spine morphogenesis
GO:0071625 IEA vocalization behavior
GO:0097104 IMP postsynaptic membrane assembly
GO:0097105 ISS presynaptic membrane assembly
GO:1900271 IMP regulation of long-term synaptic potentiation
GO:2000310 IMP regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311 IMP regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000331 IMP regulation of terminal button organization
GO:2000463 IMP positive regulation of excitatory postsynaptic membrane potential
GO:2000969 IMP positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062376 nlgn3b neuroligin 3b protein_coding Danio_rerio
ENSDARG00000062581 nlgn3a neuroligin 3a protein_coding Danio_rerio
ENSG00000196338 NLGN3 neuroligin 3 protein_coding Homo_sapiens

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