C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mcf.2 transforming sequence-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031442 Mcf2l 10090 + 8:12873806-13020905 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000095456 Mcf2l-009 12873827-13019053 protein_coding
  ENSMUST00000098927 Mcf2l-019 12926632-13018177 protein_coding
  ENSMUST00000110866 Mcf2l-004 12949484-13020501 protein_coding
  ENSMUST00000110867 Mcf2l-003 12949416-13019275 protein_coding
  ENSMUST00000110871 Mcf2l-017 12947953-13014029 protein_coding
  ENSMUST00000110873 Mcf2l-018 12984276-13017468 protein_coding
  ENSMUST00000110876 Mcf2l-001 12915893-13020509 protein_coding
  ENSMUST00000110879 Mcf2l-014 12915975-13019309 protein_coding
  ENSMUST00000123811 Mcf2l-022 13011494-13020527 protein_coding
  ENSMUST00000126905 Mcf2l-008 13000759-13020505 protein_coding
  ENSMUST00000127229 Mcf2l-012 13013062-13015365 retained_intron
  ENSMUST00000130302 Mcf2l-005 12947919-12988152 retained_intron
  ENSMUST00000134227 Mcf2l-015 13011510-13018094 protein_coding
  ENSMUST00000134989 Mcf2l-013 13017176-13019007 retained_intron
  ENSMUST00000138387 Mcf2l-011 12873948-12890108 processed_transcript
  ENSMUST00000139776 Mcf2l-021 13013561-13018999 protein_coding
  ENSMUST00000145067 Mcf2l-006 12984296-13020505 protein_coding
  ENSMUST00000145892 Mcf2l-020 13011818-13017439 protein_coding
  ENSMUST00000156405 Mcf2l-002 12915911-12992161 processed_transcript
  ENSMUST00000156560 Mcf2l-010 12873806-12880146 protein_coding
  ENSMUST00000173006 Mcf2l-007 12984281-13011546 protein_coding
  ENSMUST00000173099 Mcf2l-016 12915256-13020905 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000095456ENSMUST00000098927ENSMUST00000110866ENSMUST00000110871ENSMUST00000110873ENSMUST00000110876ENSMUST00000123811ENSMUST00000126905ENSMUST00000130302ENSMUST00000134989ENSMUST00000139776ENSMUST00000145892ENSMUST00000156405ENSMUST00000173006ENSMUST00000173099
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000095456 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.585±0.00 N/A 1.282±0.42
ENSMUST00000098927 1.301±0.00 N/A N/A 24.170±0.00 1.801±0.00 N/A 2.254±0.00 N/A N/A N/A 1.244±0.40 4.730±1.78 2.796±2.59 1.963±0.71
ENSMUST00000110866 3.356±1.43 0.867±0.00 N/A N/A 1.160±0.00 5.849±0.14 1.742±0.41 1.495±0.31 0.114±0.05 3.709±0.00 1.025±0.43 0.792±0.02 1.502±0.97 0.627±0.00
ENSMUST00000110871 N/A 0.918±0.06 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.973±0.00 N/A 0.786±0.00
ENSMUST00000110873 N/A N/A N/A N/A N/A N/A N/A N/A 0.130±0.00 N/A N/A N/A N/A N/A
ENSMUST00000110876 N/A 0.731±0.11 N/A 15.493±5.02 N/A 5.010±0.00 N/A N/A N/A N/A N/A 0.591±0.00 0.778±0.22 N/A
ENSMUST00000123811 7.808±0.27 N/A 1.151±0.34 11.915±0.00 N/A 9.743±2.63 3.779±0.51 2.331±0.00 0.128±0.08 7.816±1.65 1.940±0.67 3.171±0.18 2.022±0.67 1.020±0.21
ENSMUST00000126905 N/A 1.356±0.21 0.308±0.00 N/A N/A N/A N/A N/A 0.040±0.01 N/A 0.761±0.40 N/A N/A N/A
ENSMUST00000130302 N/A N/A N/A N/A N/A N/A N/A N/A 0.011±0.00 N/A N/A N/A N/A N/A
ENSMUST00000134989 N/A N/A N/A N/A N/A N/A N/A N/A 0.169±0.05 N/A N/A N/A N/A N/A
ENSMUST00000139776 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.077±0.00
ENSMUST00000145892 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 14.696±5.80 N/A
ENSMUST00000156405 N/A N/A N/A N/A N/A N/A N/A N/A 0.083±0.00 N/A N/A N/A N/A N/A
ENSMUST00000173006 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.877±0.00 1.329±0.00 N/A N/A
ENSMUST00000173099 1.250±0.49 0.532±0.00 N/A N/A 0.972±0.00 2.203±0.25 1.086±0.00 N/A 0.054±0.00 2.730±0.08 N/A 0.808±0.23 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014E CIL_00014E_0002 CGP 8:12757014-13020905
CIL_0000RV CIL_0000RV_0002 CGP 8:12873806-13035809

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IDA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005545 IDA 1-phosphatidylinositol binding
GO:0005615 IEA extracellular space
GO:0007266 IDA Rho protein signal transduction
GO:0016020 IDA membrane
GO:0030027 IDA lamellipodium
GO:0032321 IEA:IDA positive regulation of Rho GTPase activity
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075859 mcf2la mcf.2 cell line derived transforming sequence-like a protein_coding Danio_rerio
ENSDARG00000076480 mcf2lb mcf.2 cell line derived transforming sequence-like b protein_coding Danio_rerio
ENSG00000126217 MCF2L MCF.2 cell line derived transforming sequence-like protein_coding Homo_sapiens

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