C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000057784 Slc7a2-001 ENSMUSG00000031596 10090 + 8:40862412-40922308 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000057784
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000057784 0.781±0.00 2.607±0.74 8.368±2.46 0.200±0.09 0.292±0.22 0.657±0.20 27.716±23.68 1.592±0.57 6.604±2.62 2.796±0.00 2.277±2.79 0.258±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001TT CIL_0001TT_0002 CGP 8:40862396-40990785

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000064 IDA L-ornithine transmembrane transporter activity
GO:0002537 IMP nitric oxide production involved in inflammatory response
GO:0005289 IDA high-affinity arginine transmembrane transporter activity
GO:0005292 IDA high-affinity lysine transmembrane transporter activity
GO:0006809 IMP nitric oxide biosynthetic process
GO:0015181 IMP arginine transmembrane transporter activity
GO:0015189 IDA L-lysine transmembrane transporter activity
GO:0016021 IDA integral component of membrane
GO:0042116 IMP macrophage activation
GO:0043030 IMP regulation of macrophage activation
GO:0050727 IMP regulation of inflammatory response
GO:0061459 IMP L-arginine transmembrane transporter activity
GO:0097626 IDA low-affinity L-arginine transmembrane transporter activity
GO:0097627 IDA high-affinity L-ornithine transmembrane transporter activity
GO:0097638 IDA L-arginine import across plasma membrane
GO:0097639 IDA L-lysine import across plasma membrane
GO:0097640 IDA L-ornithine import across plasma membrane
GO:1902023 IMP L-arginine transport
GO:1903352 IDA L-ornithine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000004531 SLC7A2-201 protein_coding Homo_sapiens 0 1860
ENST00000292579 ZNF250-001 protein_coding Homo_sapiens 0.00000005 66
ENST00000398090 SLC7A2-202 protein_coding Homo_sapiens 0 2135
ENST00000470360 SLC7A2-002 protein_coding Homo_sapiens 0 2135
ENST00000494857 SLC7A2-001 protein_coding Homo_sapiens 0 1860
ENST00000522656 SLC7A2-003 protein_coding Homo_sapiens 0 1860

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