C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SMAD family member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031681 Smad1 10090 - 8:79338395-79399518 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066081 Smad1-003 79355356-79399518 protein_coding
  ENSMUST00000066091 Smad1-001 79338395-79399518 protein_coding
  ENSMUST00000109885 Smad1-002 79341580-79399518 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066081ENSMUST00000066091ENSMUST00000109885
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066081 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.681±0.00 N/A
ENSMUST00000066091 16.383±5.29 10.256±0.70 12.253±2.03 16.861±9.17 11.806±3.32 23.591±2.55 5.087±1.20 6.546±0.34 4.939±1.44 11.040±1.55 2.791±0.18 19.593±4.21 5.514±3.27 4.236±2.43
ENSMUST00000109885 1.232±0.00 N/A N/A N/A 0.834±0.24 N/A 0.368±0.00 N/A N/A 1.188±0.07 0.310±0.02 1.489±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001657 IEP ureteric bud development
GO:0001710 IGI mesodermal cell fate commitment
GO:0001822 IEA kidney development
GO:0002051 IGI osteoblast fate commitment
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005637 IEA nuclear inner membrane
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0006954 IEP inflammatory response
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007183 IEA SMAD protein complex assembly
GO:0007276 IMP gamete generation
GO:0008285 IMP negative regulation of cell proliferation
GO:0009880 ISS embryonic pattern specification
GO:0010243 IEA response to organonitrogen compound
GO:0010628 IMP positive regulation of gene expression
GO:0010656 IEA negative regulation of muscle cell apoptotic process
GO:0019901 IEA protein kinase binding
GO:0030509 TAS BMP signaling pathway
GO:0030901 IMP midbrain development
GO:0030902 IMP hindbrain development
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0042592 IMP homeostatic process
GO:0042802 IEA identical protein binding
GO:0043234 ISO protein complex
GO:0045597 IEA positive regulation of cell differentiation
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0050775 IEA positive regulation of dendrite morphogenesis
GO:0051216 IGI cartilage development
GO:0060038 IGI cardiac muscle cell proliferation
GO:0060348 IGI bone development
GO:0061036 IDA positive regulation of cartilage development
GO:0070410 IEA co-SMAD binding
GO:0070411 IEA I-SMAD binding
GO:0071407 IDA cellular response to organic cyclic compound
GO:0071773 IGI cellular response to BMP stimulus
GO:1901522 IGI positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000170365 SMAD1 SMAD family member 1 protein_coding Homo_sapiens

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