C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SMAD family member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000066091 Smad1-001 ENSMUSG00000031681 10090 - 8:79338395-79399518 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066091
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066091 16.383±5.29 10.256±0.70 12.253±2.03 16.861±9.17 11.806±3.32 23.591±2.55 5.087±1.20 6.546±0.34 4.939±1.44 11.040±1.55 2.791±0.18 19.593±4.21 5.514±3.27 4.236±2.43

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001657 IEP ureteric bud development
GO:0001710 IGI mesodermal cell fate commitment
GO:0001822 IEA kidney development
GO:0002051 IGI osteoblast fate commitment
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005637 IEA nuclear inner membrane
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0006954 IEP inflammatory response
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007183 IEA SMAD protein complex assembly
GO:0007276 IMP gamete generation
GO:0008285 IMP negative regulation of cell proliferation
GO:0009880 ISS embryonic pattern specification
GO:0010243 IEA response to organonitrogen compound
GO:0010628 IMP positive regulation of gene expression
GO:0010656 IEA negative regulation of muscle cell apoptotic process
GO:0019901 IEA protein kinase binding
GO:0030509 ISS BMP signaling pathway
GO:0030901 IMP midbrain development
GO:0030902 IMP hindbrain development
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0042592 IMP homeostatic process
GO:0042802 IEA identical protein binding
GO:0043234 ISO protein complex
GO:0045597 IEA positive regulation of cell differentiation
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0050775 IEA positive regulation of dendrite morphogenesis
GO:0051216 IGI cartilage development
GO:0060038 IGI cardiac muscle cell proliferation
GO:0060348 IGI bone development
GO:0061036 IDA positive regulation of cartilage development
GO:0070410 IEA co-SMAD binding
GO:0070411 IEA I-SMAD binding
GO:0071407 IDA cellular response to organic cyclic compound
GO:0071773 IGI cellular response to BMP stimulus
GO:1901522 IGI positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000129079 smad5-201 protein_coding Danio_rerio 0 850
ENSDART00000054175 smad5-001 protein_coding Danio_rerio 0 850
ENSDART00000028618 smad9-201 protein_coding Danio_rerio 0 459
ENSDART00000132823 smad9-001 protein_coding Danio_rerio 0 459
ENSDART00000138281 smad9-003 retained_intron Danio_rerio 0 268
ENSDART00000145509 smad9-002 processed_transcript Danio_rerio 1.4013e-45 189
ENST00000302085 SMAD1-001 protein_coding Homo_sapiens 0 1879
ENST00000394092 SMAD1-015 protein_coding Homo_sapiens 0 1733
ENST00000506626 SMAD1-017 processed_transcript Homo_sapiens 1e-28 130
ENST00000510948 SMAD1-018 processed_transcript Homo_sapiens 0 562
ENST00000511125 SMAD1-014 retained_intron Homo_sapiens 0 883
ENST00000511255 SMAD1-019 retained_intron Homo_sapiens 0 457
ENST00000512019 SMAD1-007 protein_coding Homo_sapiens 0 527
ENST00000514777 SMAD5-011 processed_transcript Homo_sapiens 0 424
ENST00000515385 SMAD1-002 protein_coding Homo_sapiens 0 1869
ENST00000515527 SMAD1-016 processed_transcript Homo_sapiens 1.4013e-45 187
ENST00000545279 SMAD5-001 protein_coding Homo_sapiens 0 809
ENST00000545620 SMAD5-201 protein_coding Homo_sapiens 0 809

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