C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin light chain kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031698 Mylk3 10090 - 8:85324303-85386345 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034133 Mylk3-001 85324303-85365324 protein_coding
  ENSMUST00000121972 Mylk3-002 85327053-85365347 protein_coding
  ENSMUST00000122452 Mylk3-003 85324447-85380978 protein_coding
  ENSMUST00000137290 Mylk3-005 85359248-85386345 protein_coding
  ENSMUST00000138825 Mylk3-004 85360425-85381034 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034133ENSMUST00000121972ENSMUST00000122452ENSMUST00000137290ENSMUST00000138825
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034133 0.068±0.00 N/A N/A 0.006±0.00 0.052±0.03 N/A 43.965±13.27 0.084±0.02 2.147±0.84 0.667±0.15 0.080±0.00 N/A 0.904±0.71 0.040±0.00
ENSMUST00000121972 N/A N/A N/A 0.029±0.00 0.184±0.06 0.091±0.03 31.216±11.49 0.117±0.00 0.111±0.05 0.681±0.00 0.065±0.00 0.330±0.16 0.231±0.00 0.373±0.00
ENSMUST00000122452 0.070±0.03 0.116±0.04 0.064±0.01 0.023±0.01 0.064±0.03 0.052±0.02 27.810±0.00 0.306±0.10 9.438±6.26 1.023±0.16 0.061±0.04 0.485±0.21 1.026±0.57 0.278±0.18
ENSMUST00000137290 N/A N/A N/A 1.011±0.00 N/A N/A N/A N/A N/A N/A 0.211±0.00 N/A N/A N/A
ENSMUST00000138825 N/A N/A N/A N/A N/A N/A N/A N/A 0.209±0.01 N/A N/A 1.806±0.62 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00044W CIL_00044W_0003 CGP 8:85299632-85386345
CIL_00044Z CIL_00044Z_0003 CGP 8:85324303-85432841

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002528 IEA regulation of vascular permeability involved in acute inflammatory response
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004683 IDA calmodulin-dependent protein kinase activity
GO:0004687 IDA myosin light chain kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0006468 IDA protein phosphorylation
GO:0015629 IDA actin cytoskeleton
GO:0045214 IDA sarcomere organization
GO:0048769 IEA sarcomerogenesis
GO:0055003 IEA cardiac myofibril assembly
GO:0060298 IEA positive regulation of sarcomere organization
GO:0071347 IEA cellular response to interleukin-1

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076348 mylk3 myosin light chain kinase 3 protein_coding Danio_rerio
ENSG00000140795 MYLK3 myosin light chain kinase 3 protein_coding Homo_sapiens

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