C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: meiotic recombination 11 homolog A (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031928 Mre11a 10090 + 9:14784654-14837123 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034405 Mre11a-001 14784654-14834646 protein_coding
  ENSMUST00000115632 Mre11a-002 14784676-14837123 protein_coding
  ENSMUST00000136568 Mre11a-004 14797166-14803853 protein_coding
  ENSMUST00000147305 Mre11a-003 14784702-14799620 protein_coding
  ENSMUST00000147676 Mre11a-005 14797153-14811939 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034405ENSMUST00000115632ENSMUST00000147305
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034405 N/A N/A 0.888±0.07 1.042±0.29 N/A 0.776±0.10 N/A 0.330±0.00 2.176±1.44 0.792±0.00 0.746±0.19 2.197±1.37 4.065±2.52 4.618±2.28
ENSMUST00000115632 N/A 0.527±0.11 1.757±0.02 2.290±0.14 0.788±0.45 N/A 0.665±0.03 N/A 2.457±0.80 0.805±0.30 0.506±0.15 1.545±0.70 1.185±0.41 1.102±0.26
ENSMUST00000147305 1.572±0.00 1.759±0.01 N/A N/A 3.412±0.00 1.747±0.00 1.400±0.21 N/A 1.063±0.25 N/A N/A N/A N/A 3.310±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IBA telomere maintenance
GO:0000781 IEA chromosome, telomeric region
GO:0000785 IBA chromatin
GO:0003677 IEA DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004519 IBA endonuclease activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006284 IBA base-excision repair
GO:0006289 IBA nucleotide-excision repair
GO:0006302 IMP double-strand break repair
GO:0006974 ISO cellular response to DNA damage stimulus
GO:0007062 IEA sister chromatid cohesion
GO:0007095 IMP mitotic G2 DNA damage checkpoint
GO:0007129 IMP synapsis
GO:0008022 IEA protein C-terminus binding
GO:0008283 IMP cell proliferation
GO:0008408 IBA 3'-5' exonuclease activity
GO:0030145 IEA manganese ion binding
GO:0030870 IBA Mre11 complex
GO:0031573 IMP intra-S DNA damage checkpoint
GO:0031954 IEA positive regulation of protein autophosphorylation
GO:0032508 IEA DNA duplex unwinding
GO:0032876 IEA negative regulation of DNA endoreduplication
GO:0033674 IEA positive regulation of kinase activity
GO:0035861 IBA site of double-strand break
GO:0051276 IMP chromosome organization
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000020922 MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) protein_coding Homo_sapiens

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