C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: meiotic recombination 11 homolog A (S. cerevisiae)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000115632 Mre11a-002 ENSMUSG00000031928 10090 + 9:14784676-14837123 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastHeartLiverLungMuscleOvaryPlacentaTestisENSMUST00000115632
Transcript ID Adrenal Bladder Brain Breast Heart Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000115632 0.527±0.11 1.757±0.02 2.290±0.14 0.788±0.45 0.665±0.03 2.457±0.80 0.805±0.30 0.506±0.15 1.545±0.70 1.185±0.41 1.102±0.26

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000723 IBA telomere maintenance
GO:0000785 IBA chromatin
GO:0004519 IBA endonuclease activity
GO:0005634 IDA nucleus
GO:0006284 IBA base-excision repair
GO:0006289 IBA nucleotide-excision repair
GO:0006302 IMP double-strand break repair
GO:0006974 ISO cellular response to DNA damage stimulus
GO:0007095 IMP mitotic G2 DNA damage checkpoint
GO:0007129 IMP synapsis
GO:0008283 IMP cell proliferation
GO:0008408 IBA 3'-5' exonuclease activity
GO:0030145 IEA manganese ion binding
GO:0030870 IBA Mre11 complex
GO:0031573 IMP intra-S DNA damage checkpoint
GO:0035861 IBA site of double-strand break
GO:0051276 IMP chromosome organization
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000323929 MRE11A-001 protein_coding Homo_sapiens 0 1131
ENST00000323977 MRE11A-002 protein_coding Homo_sapiens 0 1131
ENST00000393241 MRE11A-006 protein_coding Homo_sapiens 0 1131
ENST00000407439 MRE11A-004 protein_coding Homo_sapiens 0 1094
ENST00000464884 RP11-294L13.1-001 processed_pseudogene Homo_sapiens 0 904
ENST00000536144 MRE11A-011 processed_transcript Homo_sapiens 0 370
ENST00000536754 MRE11A-007 protein_coding Homo_sapiens 0 455
ENST00000538923 MRE11A-008 protein_coding Homo_sapiens 0 403
ENST00000540013 MRE11A-005 protein_coding Homo_sapiens 0 811
ENST00000541157 MRE11A-010 processed_transcript Homo_sapiens 0 372

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