C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: meiotic recombination 11 homolog A (S. cerevisiae)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034405 Mre11a-001 ENSMUSG00000031928 10090 + 9:14784654-14834646 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034405
Transcript ID Bladder Brain Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034405 0.888±0.07 1.042±0.29 0.776±0.10 0.330±0.00 2.176±1.44 0.792±0.00 0.746±0.19 2.197±1.37 4.065±2.52 4.618±2.28

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000723 IBA telomere maintenance
GO:0000781 IEA chromosome, telomeric region
GO:0000785 IBA chromatin
GO:0003677 IEA DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004519 IBA endonuclease activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006284 IBA base-excision repair
GO:0006289 IBA nucleotide-excision repair
GO:0006302 IMP double-strand break repair
GO:0006974 ISO cellular response to DNA damage stimulus
GO:0007062 IEA sister chromatid cohesion
GO:0007095 IMP mitotic G2 DNA damage checkpoint
GO:0007129 IMP synapsis
GO:0008022 IEA protein C-terminus binding
GO:0008283 IMP cell proliferation
GO:0008408 IBA 3'-5' exonuclease activity
GO:0030145 IEA manganese ion binding
GO:0030870 IBA Mre11 complex
GO:0031573 IMP intra-S DNA damage checkpoint
GO:0031954 IEA positive regulation of protein autophosphorylation
GO:0032508 IEA DNA duplex unwinding
GO:0032876 IEA negative regulation of DNA endoreduplication
GO:0033674 IEA positive regulation of kinase activity
GO:0035861 IBA site of double-strand break
GO:0051276 IMP chromosome organization
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000323929 MRE11A-001 protein_coding Homo_sapiens 0 2049
ENST00000323977 MRE11A-002 protein_coding Homo_sapiens 0 1827
ENST00000393241 MRE11A-006 protein_coding Homo_sapiens 0 2063
ENST00000407439 MRE11A-004 protein_coding Homo_sapiens 0 2012
ENST00000464884 RP11-294L13.1-001 processed_pseudogene Homo_sapiens 0 1535
ENST00000536144 MRE11A-011 processed_transcript Homo_sapiens 0 370
ENST00000536754 MRE11A-007 protein_coding Homo_sapiens 0 455
ENST00000538923 MRE11A-008 protein_coding Homo_sapiens 0 403
ENST00000540013 MRE11A-005 protein_coding Homo_sapiens 0 811
ENST00000541157 MRE11A-010 processed_transcript Homo_sapiens 0 372

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