C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-box 20
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031965 Tbx20 10090 - 9:24720812-24774303 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000052946 Tbx20-201 24720812-24774303 protein_coding
  ENSMUST00000166018 Tbx20-202 24740256-24774303 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000052946ENSMUST00000166018
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000052946 0.016±0.00 5.019±0.48 6.144±0.05 0.276±0.15 0.006±0.00 19.635±1.34 0.029±0.02 0.570±0.07 1.141±0.27 0.011±0.00 0.024±0.02 2.120±1.81 0.011±0.01
ENSMUST00000166018 N/A N/A N/A N/A N/A N/A 0.025±0.02 N/A N/A N/A 0.011±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SV CIL_0008SV_0002 VISTA 9:24420490-25021595
CIL_0008SU CIL_0008SU_0002 VISTA 9:24437085-25037801
CIL_00091I CIL_00091I_0002 VISTA 9:24448244-25049108
CIL_00091J CIL_00091J_0002 VISTA 9:24454514-25055359
CIL_00091K CIL_00091K_0002 VISTA 9:24489002-25089893
CIL_00091G CIL_00091G_0002 VISTA 9:24502515-25103444
CIL_0008SW CIL_0008SW_0002 VISTA 9:24511552-25112154
CIL_00091H CIL_00091H_0002 VISTA 9:24533559-25134351
CIL_0008SR CIL_0008SR_0002 VISTA 9:24560616-25161316
CIL_0009CB CIL_0009CB_0002 VISTA 9:24587072-25190068
CIL_00084T CIL_00084T_0002 VISTA 9:24587105-25190036
CIL_00091N CIL_00091N_0002 VISTA 9:24619749-25221117
CIL_0008SX CIL_0008SX_0002 VISTA 9:24622166-25223116
CIL_00091M CIL_00091M_0002 VISTA 9:24673917-25275039

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0001569 IMP patterning of blood vessels
GO:0001764 IMP neuron migration
GO:0001947 IMP heart looping
GO:0003143 IMP embryonic heart tube morphogenesis
GO:0003148 IMP outflow tract septum morphogenesis
GO:0003151 IMP outflow tract morphogenesis
GO:0003175 IMP tricuspid valve development
GO:0003176 IMP aortic valve development
GO:0003180 IEA aortic valve morphogenesis
GO:0003193 IMP pulmonary valve formation
GO:0003203 IMP endocardial cushion morphogenesis
GO:0003207 IMP cardiac chamber formation
GO:0003215 IMP cardiac right ventricle morphogenesis
GO:0003272 IMP endocardial cushion formation
GO:0003279 IMP cardiac septum development
GO:0003344 IMP pericardium morphogenesis
GO:0003677 IDA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006936 IMP muscle contraction
GO:0008015 IMP blood circulation
GO:0008283 IMP cell proliferation
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010717 NAS regulation of epithelial to mesenchymal transition
GO:0010991 IDA negative regulation of SMAD protein complex assembly
GO:0021524 IMP visceral motor neuron differentiation
GO:0035050 IGI embryonic heart tube development
GO:0035922 IEA foramen ovale closure
GO:0036306 IMP embryonic heart tube elongation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0055008 IMP cardiac muscle tissue morphogenesis
GO:0060045 IMP positive regulation of cardiac muscle cell proliferation
GO:0060413 IEA atrial septum morphogenesis
GO:0060577 IEA pulmonary vein morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005150 tbx20 T-box 20 protein_coding Danio_rerio
ENSG00000164532 TBX20 T-box 20 protein_coding Homo_sapiens

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