C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: insulin related protein 2 (islet 2)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032318 Isl2 10090 + 9:55538672-55546180 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034869 Isl2-001 55541148-55546180 protein_coding
  ENSMUST00000114290 Isl2-002 55541207-55546180 nonsense_mediated_decay
  ENSMUST00000164373 Isl2-003 55541207-55546178 nonsense_mediated_decay
  ENSMUST00000165302 Isl2-005 55542336-55544280 retained_intron
  ENSMUST00000175950 Isl2-004 55538672-55542570 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000034869ENSMUST00000114290ENSMUST00000164373ENSMUST00000165302ENSMUST00000175950
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000034869 0.146±0.02 N/A 0.112±0.06 0.519±0.31 N/A 1.242±0.30 N/A 0.017±0.00 0.095±0.07 N/A 0.200±0.13 0.143±0.00 N/A
ENSMUST00000114290 0.010±0.00 0.016±0.00 N/A 0.018±0.00 0.016±0.01 N/A 0.016±0.00 0.004±0.00 N/A 0.008±0.00 0.168±0.13 0.512±0.62 N/A
ENSMUST00000164373 0.012±0.00 0.005±0.00 N/A 0.014±0.00 0.023±0.01 N/A 0.017±0.01 0.015±0.00 N/A 0.009±0.00 0.135±0.16 0.118±0.10 0.160±0.00
ENSMUST00000165302 0.212±0.00 N/A N/A N/A 0.081±0.01 1.360±0.27 N/A N/A N/A 0.098±0.05 0.560±0.34 N/A 0.378±0.05
ENSMUST00000175950 N/A N/A N/A N/A N/A N/A N/A 0.055±0.01 N/A N/A N/A 0.088±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000248 CIL_000248_0002 CGP 9:55454508-55546180
CIL_000245 CIL_000245_0002 CGP 9:55538672-55919605

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005622 IDA intracellular
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0021520 IGI spinal cord motor neuron cell fate specification
GO:0021524 IGI visceral motor neuron differentiation
GO:0031290 IMP retinal ganglion cell axon guidance
GO:0043565 IEA sequence-specific DNA binding
GO:0045665 IGI negative regulation of neuron differentiation
GO:0048663 IGI neuron fate commitment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003971 isl2a islet2a protein_coding Danio_rerio
ENSDARG00000053499 isl2b islet2b protein_coding Danio_rerio
ENSG00000159556 ISL2 ISL LIM homeobox 2 protein_coding Homo_sapiens

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