C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuroplastin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032336 Nptn 10090 + 9:58582240-58657955 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085651 Nptn-001 58582292-58652878 protein_coding
  ENSMUST00000114121 Nptn-201 58582407-58651318 protein_coding
  ENSMUST00000175945 Nptn-009 58582407-58643806 nonsense_mediated_decay
  ENSMUST00000176126 Nptn-008 58582444-58643668 processed_transcript
  ENSMUST00000176250 Nptn-005 58629106-58655208 protein_coding
  ENSMUST00000176557 Nptn-012 58582406-58652878 protein_coding
  ENSMUST00000176896 Nptn-010 58582441-58651962 nonsense_mediated_decay
  ENSMUST00000176916 Nptn-006 58629105-58657955 nonsense_mediated_decay
  ENSMUST00000177020 Nptn-011 58651976-58652818 processed_transcript
  ENSMUST00000177021 Nptn-004 58650199-58652057 retained_intron
  ENSMUST00000177064 Nptn-007 58582436-58651318 protein_coding
  ENSMUST00000177292 Nptn-003 58582240-58651318 protein_coding
  ENSMUST00000177380 Nptn-002 58582374-58640680 non_stop_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000085651ENSMUST00000114121ENSMUST00000176557ENSMUST00000176896ENSMUST00000176916ENSMUST00000177020ENSMUST00000177064ENSMUST00000177292ENSMUST00000177380
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000085651 26.615±4.59 N/A 68.126±6.81 28.757±2.40 12.165±2.72 N/A N/A 14.299±0.80 45.350±13.28 13.578±0.98 6.205±0.78 14.985±10.16 24.332±17.37 4.475±1.18
ENSMUST00000114121 38.204±5.43 N/A 77.062±0.00 N/A 69.631±29.89 72.965±42.88 21.263±2.57 61.254±10.72 10.114±1.70 89.380±29.13 N/A 68.545±37.28 N/A 10.843±2.27
ENSMUST00000176557 11.215±0.00 N/A 80.823±2.87 27.919±12.40 10.104±3.34 13.292±0.00 21.318±1.19 15.171±0.80 6.727±1.16 17.062±0.37 25.546±1.73 14.507±8.47 10.296±4.19 3.932±1.76
ENSMUST00000176896 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 42.345±0.00 24.958±4.74 N/A
ENSMUST00000176916 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.720±0.87
ENSMUST00000177020 N/A N/A N/A 104.961±0.00 N/A N/A N/A N/A N/A N/A N/A 22.390±0.00 31.606±10.22 N/A
ENSMUST00000177064 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.759±0.00 N/A 8.898±0.00
ENSMUST00000177292 N/A N/A N/A 54.049±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000177380 180.420±14.19 174.601±17.45 N/A 217.360±138.16 58.816±22.36 109.114±46.14 90.890±25.63 114.162±30.31 76.237±49.07 74.335±31.50 N/A 100.645±50.03 96.369±10.78 21.449±4.96

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0005105 ISS type 1 fibroblast growth factor receptor binding
GO:0007156 ISS homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0009986 IEA cell surface
GO:0010976 ISS positive regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0042734 ISS presynaptic membrane
GO:0045743 ISS positive regulation of fibroblast growth factor receptor signaling pathway
GO:0048170 ISS positive regulation of long-term neuronal synaptic plasticity
GO:0050839 ISS cell adhesion molecule binding
GO:0060291 ISS long-term synaptic potentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043864 nptnb neuroplastin b protein_coding Danio_rerio
ENSDARG00000089817 NPTN (2 of 2) neuroplastin protein_coding Danio_rerio
ENSG00000156642 NPTN neuroplastin protein_coding Homo_sapiens

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