C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: anterior pharynx defective 1b homolog (C. elegans)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032375 Aph1b 10090 - 9:66775202-66795490 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034934 Aph1b-001 66775202-66795490 protein_coding
  ENSMUST00000113730 Aph1b-003 66779193-66795376 protein_coding
  ENSMUST00000168309 Aph1b-002 66775209-66795436 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034934ENSMUST00000113730ENSMUST00000168309
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034934 2.267±0.67 4.055±2.32 3.397±0.30 5.361±3.24 1.670±0.32 2.616±0.79 1.154±0.38 3.218±0.34 0.504±0.18 3.467±0.39 0.590±0.16 3.468±2.30 1.398±0.61 0.457±0.09
ENSMUST00000113730 N/A N/A N/A N/A N/A N/A N/A N/A 0.452±0.09 N/A N/A N/A N/A N/A
ENSMUST00000168309 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.334±0.10 0.299±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098V CIL_00098V_0002 VISTA 9:66700483-67304558
CIL_00094O CIL_00094O_0002 VISTA 9:66740666-67343521

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 IGI endopeptidase activity
GO:0005886 TAS plasma membrane
GO:0006508 IGI proteolysis
GO:0007219 IEA Notch signaling pathway
GO:0016021 IEA integral component of membrane
GO:0016485 IEA protein processing
GO:0043085 IEA positive regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005612 aph1b anterior pharynx defective 1B protein_coding Danio_rerio
ENSG00000138613 APH1B APH1B gamma secretase subunit protein_coding Homo_sapiens

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