C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytokine inducible SH2-containing protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032578 Cish 10090 + 9:107296026-107302784 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085102 Cish-001 107296026-107301987 protein_coding
  ENSMUST00000165664 Cish-003 107296907-107301943 processed_transcript
  ENSMUST00000167072 Cish-005 107296912-107300551 protein_coding
  ENSMUST00000168260 Cish-002 107296710-107302784 protein_coding
  ENSMUST00000171568 Cish-004 107299155-107300458 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000085102ENSMUST00000165664ENSMUST00000168260
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000085102 1.105±0.48 1.740±0.37 2.611±0.42 0.393±0.00 6.257±1.15 4.122±0.81 4.338±0.00 4.883±1.29 2.455±1.69 4.482±2.04 3.058±1.61 3.986±1.28 0.740±0.40 0.488±0.14
ENSMUST00000165664 2.077±1.60 1.505±0.31 1.489±0.22 0.255±0.09 4.529±1.39 2.756±0.34 4.684±0.06 3.408±1.13 1.908±1.36 7.758±0.80 2.110±1.59 5.097±5.12 0.426±0.23 0.218±0.07
ENSMUST00000168260 1.604±1.21 5.528±1.24 N/A 0.438±0.00 5.976±2.00 2.049±0.10 8.465±3.57 6.110±1.51 1.404±0.25 5.014±0.72 N/A 4.429±1.19 0.266±0.00 0.362±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D8 CIL_0008D8_0002 VISTA 9:107005935-107609958
CIL_0006UP CIL_0006UP_0002 CGP 9:107296026-107338350

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007205 IDA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0009968 IEA negative regulation of signal transduction
GO:0016567 IEA protein ubiquitination
GO:0035556 IEA intracellular signal transduction
GO:0040008 IEA regulation of growth

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016773 cishb cytokine inducible SH2-containing protein b protein_coding Danio_rerio
ENSDARG00000060316 cish cytokine inducible SH2-containing protein protein_coding Danio_rerio
ENSG00000114737 CISH cytokine inducible SH2-containing protein protein_coding Homo_sapiens

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