C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: two pore channel 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032741 Tpcn1 10090 - 5:120534160-120588613 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000046426 Tpcn1-201 120534160-120588613 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046426
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046426 15.569±8.10 14.221±1.65 20.964±2.14 6.971±3.01 18.688±2.91 40.944±1.69 9.498±1.37 55.481±1.58 17.237±3.82 16.343±1.47 12.999±2.10 15.126±3.98 33.759±10.96 4.020±1.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000842 CIL_000842_0002 VISTA 5:119987382-120588927

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IBA voltage-gated calcium channel activity
GO:0005515 IEA protein binding
GO:0005765 ISS lysosomal membrane
GO:0005886 IBA plasma membrane
GO:0006816 IBA calcium ion transport
GO:0010008 ISS endosome membrane
GO:0016021 IEA integral component of membrane
GO:0034220 IBA ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042802 IEA identical protein binding
GO:0070588 IEA calcium ion transmembrane transport
GO:0072345 ISS NAADP-sensitive calcium-release channel activity
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062362 tpcn1 two pore segment channel 1 protein_coding Danio_rerio
ENSG00000186815 TPCN1 two pore segment channel 1 protein_coding Homo_sapiens

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