C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ankyrin 2, brain
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032826 Ank2 10090 - 3:126921606-127499259 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044443 Ank2-017 126922300-126998461 protein_coding
  ENSMUST00000104965 Ank2-011 127496107-127499259 retained_intron
  ENSMUST00000182008 Ank2-003 127024774-127409021 protein_coding
  ENSMUST00000182025 Ank2-032 126940112-126955873 nonsense_mediated_decay
  ENSMUST00000182050 Ank2-010 127078119-127162237 retained_intron
  ENSMUST00000182062 Ank2-031 126937767-126956074 protein_coding
  ENSMUST00000182064 Ank2-008 126923325-127225932 protein_coding
  ENSMUST00000182078 Ank2-022 126921612-126976086 protein_coding
  ENSMUST00000182112 Ank2-028 126921612-127339152 protein_coding
  ENSMUST00000182118 Ank2-024 126923912-126929812 protein_coding
  ENSMUST00000182212 Ank2-025 126925588-126928367 retained_intron
  ENSMUST00000182271 Ank2-033 126933196-126935117 retained_intron
  ENSMUST00000182316 Ank2-006 127336394-127499001 retained_intron
  ENSMUST00000182452 Ank2-030 127052769-127408999 protein_coding
  ENSMUST00000182547 Ank2-004 127024852-127409031 protein_coding
  ENSMUST00000182571 Ank2-023 126923913-126929812 protein_coding
  ENSMUST00000182588 Ank2-014 126921608-127408994 protein_coding
  ENSMUST00000182594 Ank2-013 126923957-127499115 protein_coding
  ENSMUST00000182610 Ank2-016 127031842-127408967 protein_coding
  ENSMUST00000182662 Ank2-026 126923957-127225932 protein_coding
  ENSMUST00000182704 Ank2-001 126921606-127409058 protein_coding
  ENSMUST00000182711 Ank2-002 126988207-127409031 protein_coding
  ENSMUST00000182726 Ank2-027 126922308-127225847 protein_coding
  ENSMUST00000182764 Ank2-020 126923602-126998418 protein_coding
  ENSMUST00000182779 Ank2-007 126923325-127225897 protein_coding
  ENSMUST00000182876 Ank2-012 127159714-127162204 retained_intron
  ENSMUST00000182959 Ank2-015 126959839-127408998 protein_coding
  ENSMUST00000182977 Ank2-021 126923861-126955967 protein_coding
  ENSMUST00000182994 Ank2-009 127031173-127162342 protein_coding
  ENSMUST00000183075 Ank2-018 126950171-126998438 retained_intron
  ENSMUST00000183095 Ank2-029 127079943-127408952 protein_coding
  ENSMUST00000183097 Ank2-019 127015303-127024248 retained_intron
  ENSMUST00000183234 Ank2-005 127334794-127408994 retained_intron
  ENSMUST00000189368 Ank2-201 127498663-127499001 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044443ENSMUST00000104965ENSMUST00000182062ENSMUST00000182064ENSMUST00000182078ENSMUST00000182112ENSMUST00000182594ENSMUST00000182704ENSMUST00000182711ENSMUST00000182726ENSMUST00000182779ENSMUST00000182959ENSMUST00000183097ENSMUST00000189368
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044443 1.607±0.74 1.297±0.26 0.790±0.00 N/A 1.192±0.58 0.521±0.08 3.194±0.00 0.583±0.00 0.461±0.30 0.627±0.12 N/A 1.935±0.51 0.867±0.31 3.822±0.00
ENSMUST00000104965 N/A 0.791±0.19 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000182062 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 73.631±0.00
ENSMUST00000182064 0.771±0.13 0.840±0.14 N/A N/A 0.735±0.18 0.626±0.00 N/A N/A 0.060±0.00 0.282±0.00 N/A 2.830±0.00 N/A 4.118±0.95
ENSMUST00000182078 N/A 1.360±0.36 0.324±0.00 25.908±0.00 1.071±0.00 N/A 3.469±0.15 0.523±0.16 0.427±0.44 N/A 1.416±0.28 N/A 0.756±0.00 N/A
ENSMUST00000182112 N/A N/A N/A 9.261±6.93 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000182594 N/A 0.429±0.13 N/A N/A N/A 0.175±0.01 N/A N/A N/A N/A N/A 0.431±0.10 N/A N/A
ENSMUST00000182704 N/A N/A N/A 1.737±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.048±0.00 N/A
ENSMUST00000182711 N/A 1.176±0.00 N/A N/A 1.288±0.00 N/A N/A N/A N/A 0.495±0.00 N/A 1.910±0.27 N/A N/A
ENSMUST00000182726 N/A N/A N/A 8.390±0.00 N/A 0.213±0.00 N/A 0.098±0.00 0.043±0.00 N/A N/A N/A N/A N/A
ENSMUST00000182779 N/A N/A N/A 2.552±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000182959 N/A 1.618±0.00 N/A N/A N/A 0.672±0.20 N/A N/A 0.150±0.00 0.360±0.06 N/A 1.883±0.62 N/A N/A
ENSMUST00000183097 N/A N/A N/A N/A N/A N/A N/A N/A 0.183±0.00 N/A N/A N/A N/A N/A
ENSMUST00000189368 N/A 14.551±5.18 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038U CIL_00038U_0002 CGP 3:126596302-127499259

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002027 IMP regulation of heart rate
GO:0003283 IEA atrial septum development
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005622 IMP intracellular
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IMP plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006874 IMP cellular calcium ion homeostasis
GO:0007165 IEA signal transduction
GO:0007399 IEA nervous system development
GO:0008104 IMP protein localization
GO:0010628 IMP positive regulation of gene expression
GO:0010881 IC regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010882 IMP regulation of cardiac muscle contraction by calcium ion signaling
GO:0014704 IDA intercalated disc
GO:0015459 IMP potassium channel regulator activity
GO:0016323 IEA basolateral plasma membrane
GO:0019899 IEA enzyme binding
GO:0019901 IEA protein kinase binding
GO:0030018 IDA Z disc
GO:0030315 IDA T-tubule
GO:0030507 IEA spectrin binding
GO:0030674 IDA protein binding, bridging
GO:0030913 IEA paranodal junction assembly
GO:0031430 IDA M band
GO:0031647 IC regulation of protein stability
GO:0031672 IDA A band
GO:0033292 IMP T-tubule organization
GO:0033365 IEA protein localization to organelle
GO:0034394 IMP protein localization to cell surface
GO:0034613 IMP cellular protein localization
GO:0036309 IMP protein localization to M-band
GO:0036371 IMP protein localization to T-tubule
GO:0042383 IDA sarcolemma
GO:0042981 RCA regulation of apoptotic process
GO:0043005 IEA neuron projection
GO:0043034 IDA costamere
GO:0043268 IMP positive regulation of potassium ion transport
GO:0044325 IPI ion channel binding
GO:0045121 IEA membrane raft
GO:0045211 IEA postsynaptic membrane
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050821 IMP protein stabilization
GO:0051117 IPI ATPase binding
GO:0051279 IEA regulation of release of sequestered calcium ion into cytosol
GO:0051597 IEA response to methylmercury
GO:0051924 IMP regulation of calcium ion transport
GO:0051928 IMP positive regulation of calcium ion transport
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060048 IMP cardiac muscle contraction
GO:0060307 IEA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0070972 IMP protein localization to endoplasmic reticulum
GO:0072659 IMP protein localization to plasma membrane
GO:0072661 IGI protein targeting to plasma membrane
GO:0086004 IMP regulation of cardiac muscle cell contraction
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086014 IMP atrial cardiac muscle cell action potential
GO:0086015 IMP SA node cell action potential
GO:0086036 IGI regulation of cardiac muscle cell membrane potential
GO:0086066 IMP atrial cardiac muscle cell to AV node cell communication
GO:0086070 IMP SA node cell to atrial cardiac muscle cell communication
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901018 IMP positive regulation of potassium ion transmembrane transporter activity
GO:1901019 IMP regulation of calcium ion transmembrane transporter activity
GO:1901021 IMP positive regulation of calcium ion transmembrane transporter activity
GO:2001257 IMP regulation of cation channel activity
GO:2001259 IMP positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009026 CR388002.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000043313 ank2b ankyrin 2b, neuronal protein_coding Danio_rerio
ENSG00000145362 ANK2 ankyrin 2, neuronal protein_coding Homo_sapiens

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