C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033006 Sox10 10090 - 15:79154913-79164490 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000040019 Sox10-201 79154913-79164490 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040019
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040019 0.632±0.11 1.519±0.33 5.085±0.69 5.000±3.72 18.173±3.73 3.255±0.51 1.100±0.34 0.356±0.09 0.164±0.24 0.614±0.09 0.597±0.27 0.295±0.20 0.031±0.00 0.481±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099H CIL_00099H_0002 VISTA 15:78863840-79464236
CIL_0008KJ CIL_0008KJ_0002 VISTA 15:78865517-79466323
CIL_0008BX CIL_0008BX_0002 VISTA 15:78873761-79474273
CIL_0008KA CIL_0008KA_0002 VISTA 15:78875821-79476550
CIL_00082J CIL_00082J_0002 VISTA 15:78908803-79509777
CIL_0008C1 CIL_0008C1_0002 VISTA 15:78918952-79520098
CIL_00082K CIL_00082K_0002 VISTA 15:78923635-79524085
CIL_0008MM CIL_0008MM_0002 VISTA 15:79023554-79624112
CIL_0007CX CIL_0007CX_0002 CGP 15:79141351-79164490
CIL_0003QD CIL_0003QD_0002 CGP 15:79154913-79256674

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001190 IGI RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001701 IGI in utero embryonic development
GO:0001755 IMP neural crest cell migration
GO:0002052 IMP positive regulation of neuroblast proliferation
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007422 IGI peripheral nervous system development
GO:0008134 IEA transcription factor binding
GO:0014015 IMP positive regulation of gliogenesis
GO:0030154 IMP cell differentiation
GO:0030318 IMP melanocyte differentiation
GO:0031315 IDA extrinsic component of mitochondrial outer membrane
GO:0042802 IEA identical protein binding
GO:0043066 IMP negative regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IGI cell maturation
GO:0048484 IMP enteric nervous system development
GO:0048546 IGI digestive tract morphogenesis
GO:0048589 IMP developmental growth
GO:0048709 IMP oligodendrocyte differentiation
GO:0048863 IEA stem cell differentiation
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077467 sox10 SRY-box containing gene 10 protein_coding Danio_rerio
ENSG00000100146 SOX10 SRY (sex determining region Y)-box 10 protein_coding Homo_sapiens

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