C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100146 SOX10 9606 - 22:37970686-37987422 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360880 SOX10-001 37972300-37987422 protein_coding
  ENST00000396884 SOX10-002 37972300-37984537 protein_coding
  ENST00000427770 SOX10-003 37977923-37984346 protein_coding
  ENST00000446929 SOX10-004 37970686-37983414 protein_coding
  ENST00000470555 SOX10-005 37978082-37984408 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonENST00000396884
Transcript ID Brain Breast Colon
ENST00000396884 34.086±27.97 20.112±0.00 11.956±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099H CIL_00099H_0001 VISTA 22:37683926-38284300
CIL_0008KJ CIL_0008KJ_0001 VISTA 22:37685616-38286450
CIL_0008BX CIL_0008BX_0001 VISTA 22:37696030-38296592
CIL_0008KA CIL_0008KA_0001 VISTA 22:37698338-38299192
CIL_00082J CIL_00082J_0001 VISTA 22:37733233-38334508
CIL_0008C1 CIL_0008C1_0001 VISTA 22:37746133-38346872
CIL_00082K CIL_00082K_0001 VISTA 22:37750385-38350990
CIL_0008MM CIL_0008MM_0001 VISTA 22:37872841-38473542
CIL_0003QJ CIL_0003QJ_0001 CGP 22:37943050-38041915
CIL_0007CX CIL_0007CX_0001 CGP 22:37952607-38041915
CIL_0003QD CIL_0003QD_0001 CGP 22:37970686-38075701

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001701 IEA in utero embryonic development
GO:0001755 IEA neural crest cell migration
GO:0002052 IEA positive regulation of neuroblast proliferation
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 TAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007422 IEA peripheral nervous system development
GO:0008134 IEA transcription factor binding
GO:0009653 TAS anatomical structure morphogenesis
GO:0014015 IEA positive regulation of gliogenesis
GO:0030154 IEA cell differentiation
GO:0030318 IEA melanocyte differentiation
GO:0031315 IEA extrinsic component of mitochondrial outer membrane
GO:0042802 IPI identical protein binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048469 IEA cell maturation
GO:0048484 IEA enteric nervous system development
GO:0048546 IEA digestive tract morphogenesis
GO:0048589 IEA developmental growth
GO:0048709 IEA oligodendrocyte differentiation
GO:0048863 IEA stem cell differentiation
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077467 sox10 SRY-box containing gene 10 protein_coding Danio_rerio
ENSMUSG00000033006 Sox10 SRY (sex determining region Y)-box 10 protein_coding Mus_musculus

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