C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual oxidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033268 Duox1 10090 + 2:122315672-122347972 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000099461 Duox1-001 122315672-122347972 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000099461
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000099461 0.164±0.04 0.067±0.04 2.852±0.10 0.062±0.02 1.020±0.19 0.106±0.05 0.153±0.05 0.073±0.04 0.003±0.00 0.770±0.28 0.102±0.03 0.113±0.06 0.068±0.02 0.037±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004QK CIL_0004QK_0003 CGP 2:122302191-122347972
CIL_0004DG CIL_0004DG_0002 CGP 2:122315672-122369162

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004601 IEA peroxidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0006590 IEA thyroid hormone generation
GO:0006979 IEA response to oxidative stress
GO:0016021 IEA integral component of membrane
GO:0016174 IEA NAD(P)H oxidase activity
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0020037 IEA heme binding
GO:0042335 IEA cuticle development
GO:0050665 IEA hydrogen peroxide biosynthetic process
GO:0055114 IEA oxidation-reduction process
GO:0072593 IGI reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062632 duox dual oxidase protein_coding Danio_rerio
ENSG00000137857 DUOX1 dual oxidase 1 protein_coding Homo_sapiens

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