C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: farnesyltransferase, CAAX box, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000041008 Fntb-001 ENSMUSG00000033373 10090 + 12:76837414-76921412 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000041008
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041008 13.667±3.03 8.031±0.97 9.551±0.54 11.747±5.88 10.023±2.22 16.851±2.53 5.139±0.75 5.215±0.22 7.160±6.24 11.109±1.64 4.979±0.37 11.868±4.93 20.871±10.99 4.604±0.43

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004311 IMP farnesyltranstransferase activity
GO:0004660 ISS protein farnesyltransferase activity
GO:0005515 IEA protein binding
GO:0005875 IEA microtubule associated complex
GO:0005965 ISS protein farnesyltransferase complex
GO:0008144 IEA drug binding
GO:0008270 ISS zinc ion binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0010035 IEA response to inorganic substance
GO:0014070 IEA response to organic cyclic compound
GO:0018343 ISS protein farnesylation
GO:0019840 IEA isoprenoid binding
GO:0034097 IEA response to cytokine
GO:0042060 IMP wound healing
GO:0042277 IEA peptide binding
GO:0043234 IEA protein complex
GO:0045787 IEA positive regulation of cell cycle
GO:0048146 IMP positive regulation of fibroblast proliferation
GO:0051770 IEA positive regulation of nitric-oxide synthase biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000246166 FNTB-001 protein_coding Homo_sapiens 0 1844
ENST00000549987 CHURC1-FNTB-001 protein_coding Homo_sapiens 0 1546
ENST00000551823 CHURC1-FNTB-003 nonsense_mediated_decay Homo_sapiens 0 305
ENST00000552941 CHURC1-FNTB-002 nonsense_mediated_decay Homo_sapiens 0 1567
ENST00000554210 FNTB-004 retained_intron Homo_sapiens 0 536
ENST00000554334 FNTB-002 retained_intron Homo_sapiens 0 941
ENST00000555372 FNTB-006 processed_transcript Homo_sapiens 0 579
ENST00000555618 FNTB-007 retained_intron Homo_sapiens 0 287
ENST00000555742 FNTB-003 processed_transcript Homo_sapiens 0 531
ENST00000556709 FNTB-005 processed_transcript Homo_sapiens 0 268
ENST00000557300 FNTB-008 retained_intron Homo_sapiens 0 446

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