C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, class 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033628 Pik3c3 10090 + 18:30272747-30348126 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000091978 Pik3c3-003 30272872-30343116 protein_coding
  ENSMUST00000115811 Pik3c3-004 30272870-30330968 protein_coding
  ENSMUST00000115812 Pik3c3-001 30272747-30348126 protein_coding
  ENSMUST00000131405 Pik3c3-002 30272927-30348120 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000091978ENSMUST00000115811ENSMUST00000115812ENSMUST00000131405
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000091978 N/A 0.484±0.13 N/A 2.532±0.00 0.514±0.00 N/A N/A N/A N/A N/A N/A 1.754±1.32 1.477±0.00 2.105±0.00
ENSMUST00000115811 N/A 0.274±0.00 N/A N/A N/A 0.725±0.00 N/A N/A N/A N/A N/A 0.812±0.32 N/A 0.302±0.00
ENSMUST00000115812 5.153±0.70 0.978±0.32 11.589±0.61 11.239±2.95 3.390±1.32 3.580±1.37 3.138±0.19 4.773±0.09 3.586±1.82 4.719±0.29 4.447±0.25 3.664±3.69 7.583±1.22 2.722±0.25
ENSMUST00000131405 N/A 0.880±0.00 N/A N/A 1.429±0.00 0.944±0.39 N/A N/A 0.521±0.17 N/A N/A 2.419±1.40 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003VI CIL_0003VI_0002 CGP 18:25477632-30348126
CIL_0006XU CIL_0006XU_0002 CGP 18:30272747-31317290

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IEA autophagic vacuole assembly
GO:0000910 ISS cytokinesis
GO:0004672 IMP protein kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005770 ISS late endosome
GO:0005942 IBA phosphatidylinositol 3-kinase complex
GO:0006468 IMP protein phosphorylation
GO:0007032 IEA endosome organization
GO:0016020 IEA membrane
GO:0016303 IBA 1-phosphatidylinositol-3-kinase activity
GO:0016485 IEA protein processing
GO:0030496 ISS midbody
GO:0035004 IEA phosphatidylinositol 3-kinase activity
GO:0036092 IEA phosphatidylinositol-3-phosphate biosynthetic process
GO:0043201 IEA response to leucine
GO:0045022 ISS early endosome to late endosome transport
GO:0045335 IDA phagocytic vesicle
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0050708 IEA regulation of protein secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054829 pik3c3 phosphoinositide-3-kinase, class 3 protein_coding Danio_rerio
ENSG00000078142 PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 protein_coding Homo_sapiens

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