C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol 3-kinase, catalytic subunit type 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078142 PIK3C3 9606 + 18:41955206-42087830 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262039 PIK3C3-001 41955206-42087830 protein_coding
  ENST00000398870 PIK3C3-002 41955254-42087830 protein_coding
  ENST00000585528 PIK3C3-007 41955418-41970499 protein_coding
  ENST00000586545 PIK3C3-003 41955256-41971443 protein_coding
  ENST00000587261 PIK3C3-011 42057638-42067410 retained_intron
  ENST00000587328 PIK3C3-015 42064695-42081396 retained_intron
  ENST00000587402 PIK3C3-012 42037772-42049975 protein_coding
  ENST00000588156 PIK3C3-014 42057835-42081421 retained_intron
  ENST00000588631 PIK3C3-013 42049292-42081184 retained_intron
  ENST00000589056 PIK3C3-005 42037750-42051313 protein_coding
  ENST00000589550 PIK3C3-009 41957667-41990602 retained_intron
  ENST00000590013 PIK3C3-010 42025782-42037817 processed_transcript
  ENST00000590220 PIK3C3-006 41955262-41957758 processed_transcript
  ENST00000591011 PIK3C3-008 41957639-41987875 nonsense_mediated_decay
  ENST00000593098 PIK3C3-004 42025331-42081479 retained_intron
  ENST00000597477 PIK3C3-019 42033842-42049683 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262039ENST00000398870ENST00000587328ENST00000587402ENST00000588156ENST00000589550ENST00000590013ENST00000593098ENST00000597477
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262039 1.526±0.00 2.590±0.00 0.772±0.00 4.761±0.61 1.681±0.49 1.077±0.04 0.922±0.55 0.725±0.00 N/A 1.278±0.91 0.978±0.28 1.175±0.52 0.940±0.60 1.608±0.06
ENST00000398870 N/A N/A N/A N/A N/A N/A N/A 1.688±0.00 2.382±0.00 N/A N/A 0.347±0.00 0.315±0.03 1.175±0.00
ENST00000587328 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.691±0.00 N/A N/A N/A
ENST00000587402 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.536±0.00 N/A N/A N/A N/A
ENST00000588156 N/A N/A N/A N/A N/A 6.500±0.00 N/A 6.758±0.00 3.958±0.00 2.832±0.00 N/A 9.438±0.00 5.568±0.68 16.214±0.00
ENST00000589550 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.433±0.00 7.838±0.00 11.317±0.00
ENST00000590013 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.201±0.00 14.249±0.00 20.109±0.00
ENST00000593098 N/A N/A 0.919±0.00 N/A 1.871±0.00 N/A 0.508±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000597477 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.187±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003VI CIL_0003VI_0001 CGP 18:37243047-42087830
CIL_0006XU CIL_0006XU_0001 CGP 18:41955206-43115691

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IEA autophagic vacuole assembly
GO:0000910 IMP cytokinesis
GO:0002224 TAS toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005770 IDA late endosome
GO:0005829 TAS cytosol
GO:0005930 ISS axoneme
GO:0005942 IBA phosphatidylinositol 3-kinase complex
GO:0006468 IEA protein phosphorylation
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0007032 IEA endosome organization
GO:0008286 TAS insulin receptor signaling pathway
GO:0016020 IDA membrane
GO:0016301 IEA kinase activity
GO:0016303 IMP:IEA 1-phosphatidylinositol-3-kinase activity
GO:0016485 IEA protein processing
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0030496 IDA midbody
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0035004 IEA phosphatidylinositol 3-kinase activity
GO:0036092 IEA phosphatidylinositol-3-phosphate biosynthetic process
GO:0043201 IEA response to leucine
GO:0044281 TAS small molecule metabolic process
GO:0045022 IMP early endosome to late endosome transport
GO:0045087 TAS innate immune response
GO:0045335 IEA phagocytic vesicle
GO:0046854 IEA phosphatidylinositol phosphorylation
GO:0048015 IEA phosphatidylinositol-mediated signaling
GO:0050708 IEA regulation of protein secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054829 pik3c3 phosphoinositide-3-kinase, class 3 protein_coding Danio_rerio
ENSMUSG00000033628 Pik3c3 phosphoinositide-3-kinase, class 3 protein_coding Mus_musculus

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