C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-box brain gene 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035033 Tbr1 10090 + 2:61802930-61814114 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048934 Tbr1-001 61804453-61814114 protein_coding
  ENSMUST00000102737 Tbr1-002 61806262-61812531 protein_coding
  ENSMUST00000131538 Tbr1-003 61806273-61811801 processed_transcript
  ENSMUST00000136867 Tbr1-004 61802930-61804558 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048934ENSMUST00000102737ENSMUST00000136867
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048934 0.011±0.00 0.034±0.03 0.015±0.00 12.576±7.78 0.010±0.00 N/A 0.014±0.01 0.020±0.02 0.029±0.00 0.012±0.00 0.026±0.01 0.026±0.02 0.109±0.06
ENSMUST00000102737 0.035±0.00 0.013±0.00 N/A N/A 0.055±0.02 0.027±0.01 N/A N/A 0.023±0.01 N/A 0.083±0.05 N/A 0.370±0.00
ENSMUST00000136867 N/A N/A N/A N/A 0.094±0.00 N/A 0.024±0.00 0.009±0.00 N/A N/A N/A 0.032±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008JH CIL_0008JH_0002 VISTA 2:61356142-61956716
CIL_0005L1 CIL_0005L1_0002 CGP 2:61711694-61814114
CIL_0003AH CIL_0003AH_0002 CGP 2:61802930-62326730

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007411 IMP axon guidance
GO:0010092 IMP specification of organ identity
GO:0010468 IMP regulation of gene expression
GO:0010975 IMP regulation of neuron projection development
GO:0021902 IGI commitment of neuronal cell to specific neuron type in forebrain
GO:0030182 IMP neuron differentiation
GO:0030902 IMP hindbrain development
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004712 tbr1b T-box, brain, 1b protein_coding Danio_rerio
ENSG00000136535 TBR1 T-box, brain, 1 protein_coding Homo_sapiens

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