C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G2/M-phase specific E3 ubiquitin ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035293 G2e3 10090 + 12:51348061-51376986 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054308 G2e3-001 51348061-51376986 protein_coding
  ENSMUST00000119211 G2e3-002 51348288-51373267 protein_coding
  ENSMUST00000121521 G2e3-003 51348372-51373370 protein_coding
  ENSMUST00000144767 G2e3-004 51357149-51363533 retained_intron
  ENSMUST00000152236 G2e3-005 51370675-51374077 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054308ENSMUST00000119211ENSMUST00000121521ENSMUST00000144767ENSMUST00000152236
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054308 0.563±0.47 0.673±0.14 1.441±0.13 2.811±2.18 0.439±0.18 0.766±0.20 0.198±0.00 0.377±0.14 3.238±3.06 0.614±0.15 0.234±0.05 0.995±0.45 1.786±1.25 1.263±0.28
ENSMUST00000119211 0.196±0.00 N/A N/A N/A N/A N/A 0.189±0.04 N/A 0.234±0.06 0.470±0.05 N/A 0.486±0.19 1.251±0.41 2.649±0.54
ENSMUST00000121521 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.719±0.35 0.743±0.32 N/A
ENSMUST00000144767 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.275±0.00
ENSMUST00000152236 N/A 0.455±0.06 N/A N/A N/A N/A N/A N/A 0.177±0.00 N/A N/A N/A 0.476±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005EN CIL_0005EN_0002 CGP 12:50341231-51376986
CIL_000893 CIL_000893_0002 VISTA 12:50974162-51576029
CIL_0007KV CIL_0007KV_0003 UCNEbase 12:51002016-51608860
CIL_0003SX CIL_0003SX_0002 CGP 12:51348061-51450096

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IDA protein polyubiquitination
GO:0001824 IMP blastocyst development
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006915 IEA apoptotic process
GO:0008270 IEA zinc ion binding
GO:0016874 IEA ligase activity
GO:2001243 IMP negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001313 g2e3 G2/M-phase specific E3 ubiquitin ligase protein_coding Danio_rerio
ENSG00000092140 G2E3 G2/M-phase specific E3 ubiquitin protein ligase protein_coding Homo_sapiens

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