C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G2/M-phase specific E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000092140 G2E3 9606 + 14:30559123-30620063 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000206595 G2E3-001 30559123-30620063 protein_coding
  ENST00000438909 G2E3-004 30559158-30616669 protein_coding
  ENST00000544007 G2E3-003 30559158-30607919 processed_transcript
  ENST00000547532 G2E3-012 30577756-30593639 protein_coding
  ENST00000547638 G2E3-010 30602747-30608002 processed_transcript
  ENST00000548934 G2E3-009 30598558-30615515 nonsense_mediated_decay
  ENST00000549159 G2E3-005 30611302-30618232 retained_intron
  ENST00000549553 G2E3-008 30592323-30598288 processed_transcript
  ENST00000550944 G2E3-006 30559158-30592447 protein_coding
  ENST00000552488 G2E3-007 30559160-30590963 processed_transcript
  ENST00000552515 G2E3-011 30593592-30605565 protein_coding
  ENST00000553504 G2E3-015 30559310-30616672 protein_coding
  ENST00000554714 G2E3-014 30574535-30593504 protein_coding
  ENST00000555429 G2E3-013 30577761-30589484 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000206595ENST00000438909ENST00000547532ENST00000548934ENST00000549159ENST00000552488ENST00000552515ENST00000553504
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000206595 N/A 0.425±0.00 0.648±0.21 0.583±0.32 0.553±0.22 0.238±0.09 1.167±0.00 0.587±0.00 N/A 0.493±0.00 1.463±0.56 0.555±0.40 1.852±0.52
ENST00000438909 0.511±0.00 N/A 1.051±0.00 1.306±0.60 1.193±0.00 N/A 0.313±0.00 1.531±0.00 N/A 0.030±0.00 1.946±1.63 0.582±0.23 7.293±1.95
ENST00000547532 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.812±0.00
ENST00000548934 N/A N/A N/A N/A N/A N/A N/A 0.677±0.00 N/A 1.335±0.00 N/A N/A N/A
ENST00000549159 N/A N/A 0.382±0.00 N/A 0.569±0.17 0.237±0.00 N/A 0.101±0.00 0.329±0.00 0.193±0.00 1.182±0.00 N/A N/A
ENST00000552488 N/A N/A N/A N/A N/A N/A N/A N/A 1.191±0.00 N/A N/A N/A N/A
ENST00000552515 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.568±0.00
ENST00000553504 N/A N/A N/A N/A N/A N/A N/A N/A 0.381±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005EN CIL_0005EN_0001 CGP 14:29576479-30620063
CIL_000826 CIL_000826_0001 VISTA 14:29972544-30574420
CIL_000893 CIL_000893_0001 VISTA 14:30219860-30821737
CIL_0007KV CIL_0007KV_0001 UCNEbase 14:30273158-30606663
CIL_0003SX CIL_0003SX_0001 CGP 14:30559123-30735812

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IEA protein polyubiquitination
GO:0001824 IEA blastocyst development
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006915 IEA apoptotic process
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:2001243 IEA negative regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001313 g2e3 G2/M-phase specific E3 ubiquitin ligase protein_coding Danio_rerio
ENSMUSG00000035293 G2e3 G2/M-phase specific E3 ubiquitin ligase protein_coding Mus_musculus

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