C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035632 Cnot3 10090 + 7:3645290-3661108 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038913 Cnot3-002 3645352-3661100 protein_coding
  ENSMUST00000129973 Cnot3-005 3658172-3661100 retained_intron
  ENSMUST00000132344 Cnot3-006 3651309-3655827 protein_coding
  ENSMUST00000135977 Cnot3-003 3651808-3658741 nonsense_mediated_decay
  ENSMUST00000143085 Cnot3-001 3645290-3661108 retained_intron
  ENSMUST00000144097 Cnot3-004 3658745-3661100 retained_intron
  ENSMUST00000160200 Cnot3-007 3659390-3661100 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038913ENSMUST00000129973ENSMUST00000132344ENSMUST00000135977ENSMUST00000143085
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038913 6.700±1.37 N/A 10.360±0.00 11.529±2.29 6.149±1.68 1.431±0.38 4.457±0.73 8.678±6.24 7.311±1.24 3.066±0.72 15.218±10.05 28.751±15.28 5.315±1.75
ENSMUST00000129973 N/A 9.074±1.81 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000132344 N/A N/A N/A 15.671±0.00 N/A N/A N/A N/A N/A N/A 46.679±0.00 47.631±0.00 9.414±0.00
ENSMUST00000135977 4.573±1.82 8.775±0.94 N/A 5.282±0.00 6.878±1.64 2.323±0.11 4.091±0.00 3.556±0.96 7.462±0.00 N/A 7.624±1.85 N/A 2.826±0.32
ENSMUST00000143085 N/A 3.561±0.49 N/A 3.324±0.00 N/A N/A N/A 1.746±0.54 N/A 2.091±0.67 N/A N/A 1.920±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005OD CIL_0005OD_0002 CGP 7:3629985-3661108
CIL_0001U4 CIL_0001U4_0002 CGP 7:3645290-3665840

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0001829 IMP trophectodermal cell differentiation
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0030014 ISS CCR4-NOT complex
GO:0031047 IEA gene silencing by RNA
GO:0033147 ISS negative regulation of intracellular estrogen receptor signaling pathway
GO:2000036 IMP regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007135 cnot3a CCR4-NOT transcription complex, subunit 3a protein_coding Danio_rerio
ENSDARG00000019842 cnot3b CCR4-NOT transcription complex, subunit 3b protein_coding Danio_rerio
ENSG00000088038 CNOT3 CCR4-NOT transcription complex, subunit 3 protein_coding Homo_sapiens

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