C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: synaptotagmin I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035864 Syt1 10090 - 10:108497650-109010982 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064054 Syt1-006 108497652-109010982 protein_coding
  ENSMUST00000105276 Syt1-001 108497650-109010975 protein_coding
  ENSMUST00000126278 Syt1-002 108899432-109009100 retained_intron
  ENSMUST00000146618 Syt1-003 108899215-109010962 retained_intron
  ENSMUST00000147593 Syt1-005 108627286-108636964 retained_intron
  ENSMUST00000156979 Syt1-004 108627342-109009111 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064054ENSMUST00000105276ENSMUST00000146618ENSMUST00000147593
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064054 0.102±0.03 3.518±0.00 0.301±0.08 66.298±57.40 0.080±0.05 1.173±0.04 0.128±0.08 0.199±0.22 0.089±0.07 0.090±0.02 0.053±0.00 0.931±0.37 0.032±0.02 0.040±0.01
ENSMUST00000105276 N/A N/A N/A N/A N/A N/A N/A 0.415±0.22 N/A N/A N/A N/A N/A 0.072±0.00
ENSMUST00000146618 N/A 1.159±0.46 N/A N/A 0.018±0.00 N/A N/A 0.041±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000147593 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.078±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000884 CIL_000884_0002 VISTA 10:108287857-108889362

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000149 ISS SNARE binding
GO:0001786 IEA phosphatidylserine binding
GO:0005215 IEA transporter activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005543 IEA phospholipid binding
GO:0005544 ISS calcium-dependent phospholipid binding
GO:0005546 IEA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007269 IDA neurotransmitter secretion
GO:0008021 TAS synaptic vesicle
GO:0008022 IEA protein C-terminus binding
GO:0016021 IEA integral component of membrane
GO:0016079 IMP synaptic vesicle exocytosis
GO:0017075 ISS syntaxin-1 binding
GO:0017158 IEA regulation of calcium ion-dependent exocytosis
GO:0019905 IEA syntaxin binding
GO:0030054 IEA cell junction
GO:0030141 IDA secretory granule
GO:0030276 IEA clathrin binding
GO:0030672 IDA synaptic vesicle membrane
GO:0031045 IEA dense core granule
GO:0031201 IEA SNARE complex
GO:0031340 IEA positive regulation of vesicle fusion
GO:0042734 IDA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0043005 IDA neuron projection
GO:0043229 IEA intracellular organelle
GO:0045956 IEA positive regulation of calcium ion-dependent exocytosis
GO:0048278 IEA vesicle docking
GO:0048306 IPI calcium-dependent protein binding
GO:0048791 IDA calcium ion-dependent exocytosis of neurotransmitter
GO:0050750 ISO low-density lipoprotein particle receptor binding
GO:0050806 IMP positive regulation of synaptic transmission
GO:0051592 IEA response to calcium ion
GO:0051966 IMP regulation of synaptic transmission, glutamatergic
GO:0060076 IEA excitatory synapse
GO:1903305 ISS regulation of regulated secretory pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000030614 syt1a synaptotagmin Ia protein_coding Danio_rerio
ENSDARG00000042350 syt1b synaptotagmin Ib protein_coding Danio_rerio
ENSG00000067715 SYT1 synaptotagmin I protein_coding Homo_sapiens

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