C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: seven in absentia 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036432 Siah2 10090 - 3:58674938-58692400 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070368 Siah2-001 58674938-58692400 protein_coding
  ENSMUST00000145032 Siah2-002 58676176-58686037 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070368ENSMUST00000145032
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070368 4.808±1.43 18.066±3.91 4.910±0.35 4.270±1.45 9.045±2.01 9.537±0.86 4.285±0.20 9.826±0.48 8.799±3.25 7.136±0.48 3.108±0.84 14.329±6.41 4.175±1.34 53.601±23.73
ENSMUST00000145032 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.147±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003LA CIL_0003LA_0002 CGP 3:58616300-58692400

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 TAS ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005769 IEA early endosome
GO:0005829 IEA cytosol
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0007049 IEA cell cycle
GO:0007275 IEA multicellular organismal development
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031396 IEA regulation of protein ubiquitination
GO:0031624 IEA ubiquitin conjugating enzyme binding
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043066 IEA negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044257 IEA cellular protein catabolic process
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044381 siah2l seven in absentia homolog 2 (Drosophila)-like protein_coding Danio_rerio
ENSG00000181788 SIAH2 siah E3 ubiquitin protein ligase 2 protein_coding Homo_sapiens

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